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Role of Setd2 in regulatory T cells [H3K27ac CUT&Tag]

ABSTRACT: Role of Setd2 in regulatory T cells [H3K27ac CUT&Tag]

PROVIDER: PRJNA758041 | ENA |

REPOSITORIES: ENA

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Role of Setd2 in regulatory T cells [H3K27ac CUT&Tag]

Project description:To determine the molecular regulation of Tregs by Setd2, large intestine Tregs (CD3+CD4+Foxp3-YFP+) from Setd2-deficient and control Tregs were subjected to H3K27ac CUT&Tag analysis.

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Role of Setd2 in regulatory T cells [Pol II CUT&Tag]

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Role of Setd2 in regulatory T cells

Project description:This SuperSeries is composed of the SubSeries listed below. To determine the molecular regulation of Tregs by Setd2, Spleen or large intestine Tregs (CD3+CD4+Foxp3-YFP+) were purified from littermate Foxp3Cre-YFPSetd2f/+ and Foxp3Cre-YFPSetd2f/f mice. Setd2-deficient and control Tregs were subjected to RNA-seq, RNA Polymerase II CUT&Tag or H3K27ac CUT&Tag analyses.

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