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RNA-seq data of wild-type and Abcb11-deficient mice

ABSTRACT: RNA-seq data of wild-type and Abcb11-deficient mice

PROVIDER: PRJNA761655 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR15809333_1.fastq.gz	Fastqsanger.gz
	SRR15809333_2.fastq.gz	Fastqsanger.gz
	SRR15809334_1.fastq.gz	Fastqsanger.gz
	SRR15809334_2.fastq.gz	Fastqsanger.gz
	SRR15809335_1.fastq.gz	Fastqsanger.gz

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RNA-seq data of wild-type and Abcb11-deficient mice

Project description:RNA-seq analysis were applied to elucidate the transcriptional differences of wild-type and Abcb11-deficient mice. Comparison of female Abcb11-/- (Abcb11F) and female C57BL/6J mouse (WTF) livers identified 3,652 RNA species that were differentially expressed (1,809 genes upregulated and 1,843 genes downregulated; Padj < 0.05). Comparison of liver gene expression in Abcb11F versus non-tumor tissue of female Abcb11-/- mice (NTF) revealed 47 differentially expressed genes. Cross-comparison of the lists of differentially expressed genes in Abcb11F versus WTF and in Abcb11F versus NTF revealed 36 genes common to the two data sets.

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