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Single-cell RNA-sequencing of bone marrow samples from Fsp1-Cre Col1a1flox/flox mice and WT mice

ABSTRACT: Single-cell RNA-sequencing of bone marrow samples from Fsp1-Cre Col1a1flox/flox mice and WT mice

PROVIDER: PRJNA764216 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR15931301_1.fastq.gz	Fastqsanger.gz
	SRR15931301_2.fastq.gz	Fastqsanger.gz
	SRR15931302_1.fastq.gz	Fastqsanger.gz
	SRR15931302_2.fastq.gz	Fastqsanger.gz
	SRR15931303_1.fastq.gz	Fastqsanger.gz

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Single-cell RNA-sequencing of bone marrow samples from Fsp1-Cre;Col1a1flox/flox mice and WT mice

Project description:We employed genetic mouse model (Fsp1-Cre;Col1a1flox/flox) to delete Col1a1 (type I collagen) specifically in Fsp1-expressing cells in comparison with control WT mice (Cre-negative;Col1a1flox/flox). Single-cell RNA-sequencing analyses were performed on unfractionated live cell mixtures from bone marrow samples from Fsp1-Cre;Col1a1flox/flox mice and WT mice, to investigate the impact of Fsp1-cell-specific Col1 deletion on bone marrow microenvironment.

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