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BAF complex cooperates with c-Myc to orchestrate early fate decisions of CD8 T cells (Microarray)

ABSTRACT: BAF complex cooperates with c-Myc to orchestrate early fate decisions of CD8 T cells (Microarray)

PROVIDER: PRJNA765308 | ENA |

REPOSITORIES: ENA

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BAF complex cooperates with c-Myc to orchestrate early fate decisions of CD8 T cells

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Project description:We found cBAF and c-Myc co-assort asymmetrically to the two daughter nuclei, such that daughter cells with low c-Myc and cBAF display a cell fate trajectory towards memory T cell differentiation. Moreover, cBAF complex and c-Myc physically interact with each other, and act in establishing the chromatin landscape in activated CD8 T cells.

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Project description:This SuperSeries is composed of the SubSeries listed below.

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