Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Gold polimorphism RNAseq data

PROVIDER: PRJNA766232 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR16071400_1.fastq.gz	Fastqsanger.gz
	SRR16071400_2.fastq.gz	Fastqsanger.gz
	SRR16071401_1.fastq.gz	Fastqsanger.gz
	SRR16071401_2.fastq.gz	Fastqsanger.gz
	SRR16071402_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 36

Similar Datasets

Network-based integrative analysis of lithium response in bipolar disorder using transcriptomic and GWAS data

Project description:Lithium is the gold standard treatment for bipolar disorder. The goal of this study was to identify gene expression networks associated with lithium response. RNAseq data was obtained from IPSC derived neurons from lithium responders and non-responders. Focal adhesion was the network most associated with response.

2022-06-09 | GSE205422 | GEO

RNAseq of Breast cancer PDX samples

Project description:RNAseq was done on Breast cancer PDX samples uisng Library protocol =llumina TruSeq Stranded Total RNA Kit with Ribo-Zero Gold , HiSeq 125 Cycle Paired-End Sequencing v4

2018-05-24 | GSE113476 | GEO

Illumina HiSeq Sequencing on Breast cancer PDX samples

Project description:RNAseq was done on Breast cancer PDX samples uisng Library protocol =llumina TruSeq Stranded Total RNA Kit with Ribo-Zero Gold , HiSeq 50 Cycle Single-Read Sequencing v4

2019-03-01 | GSE113986 | GEO

Gene expression profiling of macrophages: Implications for an immunosuppressive effect of dissolucytotic gold ions

Project description:Gold salts has been used in the treatment of rheumatoid arthritis but has been replaced by biologicals such as TNF-alpha inhibitors. The mechanisms behind the anti-inflammatory effect of metallic gold ions are still unknown, however, recent data showed that charged gold atoms are released from pure metallic gold implants by macrophages via a dissolucytosis membrane, and that gold ions are taken up by local macrophages, mast cells and to some extent fibroblasts. These current findings offer new treatment options for metallic gold and deeper understanding of the effect of metallic gold on key inflammatory cells as macrophages are essential. In the present study the impact of phagocytised gold ions on the global gene expression profile of the human monocytic cell line THP-1 was investigated, using microarray analysis comprising approximately 20,000 genes. The gene expression data was confirmed by measurement of three secreted proteins. A unique gene expression signature of dissolucytotic macrophages that had taken up gold ions was demonstrated. A large number of regulated genes were functionally related to immunomodulation/protection. Gold ion uptake into macrophages induced downregulation of central inflammatory cytokines as TNF-alpha, IL-32 and CD28. The data obtained in this study offer new insights into the mode of action of gold ions and suggest a future role of metallic gold as implants or topical applications in treating inflammation. To determine the effect of gold phagocytosis on global gene expression

2012-12-31 | E-GEOD-37814 | biostudies-arrayexpress

Gene expression profiling of macrophages: Implications for an immunosuppressive effect of dissolucytotic gold ions

2012-12-31 | GSE37814 | GEO

ilHypCost

Project description:Hypsopygia costalis (gold triangle), genomic and transcriptomic data

| PRJEB51263 | ENA

ilAutBrac

Project description:Autographa bractea (gold spangle), genomic and transcriptomic data

| PRJEB78791 | ENA

Project description:RNAseq data

| PRJNA715961 | ENA

Project description:RNAseq data