Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq analysis for IRF4-driven zebrafish tumors after JQ1 treatment

ABSTRACT: RNA-seq analysis for IRF4-driven zebrafish tumors after JQ1 treatment

PROVIDER: PRJNA767083 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR16102700.fastq.gz	Fastqsanger.gz
	SRR16102701.fastq.gz	Fastqsanger.gz
	SRR16102702.fastq.gz	Fastqsanger.gz
	SRR16102691.fastq.gz	Fastqsanger.gz
	SRR16102692.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

RNA-seq analysis for IRF4-driven zebrafish tumors after JQ1 treatment

Project description:RNA-seq analysis was performed using tumor cells driven by IRF4 to analyze gene expression changes after JQ1 treatment

2022-03-14 | GSE184946 | GEO

Zebrafish tumors driven by overexpression of human IRF4

Project description:Zebrafish tumors driven by overexpression of human IRF4

| PRJNA701471 | ENA

RNA-seq analysis for zebrafish tumors driven by overexpression of human IRF4

Project description:RNA-seq analysis was performed using zebrafish primary tumors and control thymus to analyze gene expression changes after IRF4 overexpression.

2022-03-14 | GSE139226 | GEO

RNA-seq analysis for zebrafish tumors driven by overexpression of human IRF4

Project description:RNA-seq analysis for zebrafish tumors driven by overexpression of human IRF4

| PRJNA578840 | ENA

H3K27ac ChIP-seq analysis for zebrafish normal thymus and tumors driven by overexpression of human IRF4

Project description:H3K27ac ChIP-seq analysis was performed using zebrafish normal thymus and primary tumors to analyze potential regulatory elements activated by IRF4 overexpression.

2022-03-14 | GSE166644 | GEO

Single cell RNA-seq analysis for normal lymphocytes and IRF4-driven zebrafish tumors

Project description:Single cell RNA-seq analysis for normal lymphocytes and IRF4-driven zebrafish tumors

| PRJNA701473 | ENA

Single cell RNA-seq analysis for normal lymphocytes and IRF4-driven zebrafish tumors

Project description:Single cell RNA-seq analysis was carried out for 1 normal sample from a control zebrafish line (lck-mCherry) and 5 non-tumor and 14 tumor samples from the IRF4 transgenic line (lck-IRF4). Tumor cells were harvested from the animals with or without heterozygous p53 mutation at different time points of tumor development.

2022-03-14 | GSE166646 | GEO

H3K27ac ChIP-seq analysis for zebrafish normal thymus and tumors driven by overexpression of human IRF4

Project description:H3K27ac ChIP-seq analysis for zebrafish normal thymus and tumors driven by overexpression of human IRF4

| PRJNA701468 | ENA

Gene expression data from NRAS-driven CNS-PNET zebrafish brain tumors and normal brain.

Project description:Zebrafish CNS-PNET tumors were generated by activating NRAS in oligoneural precursor cells. Gene expression in the zebrafish brain tumors and normal zebrafish brain was analyzed by RNA-seq.

2016-09-12 | GSE80768 | GEO

MITF deficiency accelerates GNAQ-driven uveal melanoma

Project description:Cutaneous melanoma (CM) and uveal melanoma (UM) both originate from the melanocytic lineage but are primarily driven by distinct oncogenic drivers, BRAF/NRAS or GNAQ/GNA11 respectively. The melanocytic master transcriptional regulator, MITF, is essential for both CM development and maintenance, but its role in UM is largely unexplored. Here, we use zebrafish models to dissect the key UM oncogenic signaling events, and establish the role of MITF in UM tumors. Remarkably, mitfa deficiency was profoundly UM promoting, dramatically accelerating the onset and progression of tumors induced by Tg(mitfa:GNAQQ209L);tp53M214K/M214K. To further explore the role of MITF in GNAQ-driven tumorigenesis, we performed phospho-proteomics and total proteomics on 5 zebrafish GNAQ Tg(mitfa:GNAQQ209L);tp53M214K/M214K tumors and 5 zebrafish GNAQ Tg(mitfa:GNAQQ209L);tp53M214K/M214K;mitfa-/- tumors.

2023-03-11 | PXD030527 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data