Project description:Known as “The Oriental Botanic Garden” and the natural gene bank of biological species, Shennongjia is one of the most biologically diverse areas in China and a member of UNESCO's World Network of Biosphere Reserves. The macro-organism resources of shennongjia have been deeply explored. However, the microbial community structure was scarcely detected. In this study, we aim to detedect the microbial community along six sites of Shennonajia Mountain and explore the major controlling factor in shaping microbial community with a microarray-based metagenomics tool named GeoChip 4.2.
Project description:Botanic drug CA regulated the miRNAs expression in tumor cells. We used microarrays to detail the differentiation miRNAs expression in Huh7 cells treated with CA or not.
Project description:The study involves whole exome sequencing of 20 primary tumors obtained from lung squamous carcinoma patients of Indian origin. With this, we aim to describe the mutational profile of this specific subset of lung cancer patients. This knowledge will further allow us to gain an insight into potentially actionable genomic alterations prevalent in Indian lung squamous carcinoma.
Project description:Botanic drug CA regulated the genes expression in tumor cells. We used microarrays to detail the differentiation genes expression treated with CA or not.
Project description:Botanic drug CA regulated the genes expression in tumor cells. We used microarrays to detail the differentiation genes expression treated with CA or not.
Project description:This study involves characterization of four head and neck cancer cell lines -- NT8e, OT9, AW13516 and AW8507, established from Indian head and neck cancer patients, using SNP arrays, whole exome and whole transcriptome sequencing.
Project description:The Nanostring nCounter gene expression assay was used to investigate the molecular signalling of host to Covid-19 infection, from Indian Cohort. The study revealed several biomarkers with strong predictive performance to differentiate Covid-19 infection from healthy controls and markers to differentiate between Covid-19 infection from other flu like symptoms.