Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Chikungunya virus

ABSTRACT: Genetic diversity and spatiotemporal dynamics of chikungunya infections in Mexico during the outbreak of 2014 -2016

PROVIDER: PRJNA772723 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR16493363_1.fastq.gz	Fastqsanger.gz
	SRR16493363_2.fastq.gz	Fastqsanger.gz
	SRR16493364_1.fastq.gz	Fastqsanger.gz
	SRR16493364_2.fastq.gz	Fastqsanger.gz
	SRR16493365_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 48

Similar Datasets

Chikungunya virus genome sequencing

Project description:Genomic Surveillance of Chikungunya virus from 2014 to 2016 in Bahia, Brazil

| PRJEB23556 | ENA

Chikungunya virus

Project description:Chikungunya virus Genome sequencing - Sudan outbreak 2018

| PRJNA668673 | ENA

Chikungunya virus in Italy 2017

Project description:Chikungunya virus outbreak in Italy 2017

| PRJEB23510 | ENA

Chikungunya virus

Project description:Chikungunya virus Genome sequencing

| PRJNA473275 | ENA

Chikungunya virus

Project description:Chikungunya virus genomes from Bolivia

| PRJNA609363 | ENA

Pathogenesis of chikungunya virus infection associated with fatal outcome

Project description:Chikungunya virus (CHIKV) is a mosquito-borne virus that causes acute, subacute, and chronic human diseases and can cause neurological complications and death. Here, we combined epidemiological, virological, histopathological, cytokine, molecular dynamics, metabolomics, proteomics, and genomic analyses to investigate viral and pathophysiologic factors that contribute to deaths caused by chikungunya (CHIK). Our results indicate that CHIK-deaths presented multiple organs infection, central nervous system damage, and exhibited significantly elevated serum levels of pro-inflammatory cytokines and chemokines compared to survivors. The histopathology, metabolite, and proteomic signatures of CHIK-deaths revealed hemodynamic disorders and dysregulated immune system response. CHIKV East-Central-South-African lineage caused fatal and survivor cases, and CHIKV crosses the blood–brain barrier without tight junction alterations. IFN-λ3 was highly expressed in fatal cases but did not present a direct antiviral effect on CHIKV replication in vitro. In summary, our results reveal insights to improve understanding of CHIK pathogenesis, especially the pathophysiology of fatal infections.

2024-06-16 | PXD043815 | Pride

chikungunya virus

Project description:chikungunya virus Puerto Rico-S6 metagenome

| PRJNA281533 | ENA

Chikungunya virus

Project description:Genome sequencing of Chikungunya virus from the Americas

| PRJNA294670 | ENA

Zika, dengue-1 and chikungunya strains from Guadeloupe: 2014-2016

Project description:Zika, dengue-1 and chikungunya strains isolated from patients in Guadeloupe: 2014-2016

| PRJEB37728 | ENA

Whole blood RNA-seq of pediatric cases of natural Chikungunya infection

Project description:The primary aim of this study was to characterize the transcriptomic changes between the acute and convalescent phase of natural Chikungunya infections in pediatric patients as observed in peripheral blood samples.

2018-06-13 | GSE99992 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data