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RNA sequencing of whole blood cells in patients with trigeminal neuralgia

ABSTRACT: RNA sequencing of whole blood cells in patients with trigeminal neuralgia

PROVIDER: PRJNA774204 | ENA |

REPOSITORIES: ENA

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RNA sequencing of whole blood cells in patients with trigeminal neuralgia

Project description:Trigeminal neuralgia (TN) is a type of neuropathic pain caused by injury to sensory nerves, manifesting as severe paroxysmal pain of the head and face. Trigeminal neuralgia brings a huge burden to patients, without long-term effective treatment. Changes in the expression of pain-related genes in the whole blood samples of patients play an important role in the pathogenesis, diagnosis, and evaluation of treatment effects of trigeminal neuralgia. To better understand the mechanism of trigeminal neuralgia, we collect the whole blood samples from the trigeminal neuralgia patients and the pain-free healthy comparisons. RNA-seq was conducted between the two groups to find the transcriptome changes in patients with trigeminal neuralgia.

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