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Base-resolution 5-hydroxymethylcytosine maps of sea urchin and lancelet embryos and adult tissues

ABSTRACT: Base-resolution 5-hydroxymethylcytosine maps of sea urchin and lancelet embryos and adult tissues

PROVIDER: PRJNA778390 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR16832327_1.fastq.gz	Fastqsanger.gz
	SRR16832327_2.fastq.gz	Fastqsanger.gz
	SRR16832328_1.fastq.gz	Fastqsanger.gz
	SRR16832328_2.fastq.gz	Fastqsanger.gz
	SRR16832329_1.fastq.gz	Fastqsanger.gz

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Base-resolution 5-hydroxymethylcytosine maps of sea urchin and lancelet embryos and adult tissues

Project description:This SuperSeries is composed of the SubSeries listed below.

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Project description:Glioblastoma multiforme is the most common and aggressive type of brain cancer. Little is known about the complex relationship between genomic and epigenomic as tumour progresses. We present the following base resolution whole genome maps of matched tumour/margin and blood samples from a glioblastoma multiforme patient: * Single nucleotide variations (SNVs), copy number variations (CNVs) and structural variations (SVs) as revealed by DNA sequencing. * 5-methylcytosine and 5-hydroxymethylcytosine levels obtained using (oxidative)bisulfite sequencing. * Transcript levels produced using RNA sequencing. For the three samples with very large bam raw data files ('Blood DNA-seq', 'Margin DNA-seq' and 'Tumour DNA-seq'), bai index files are available from https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-5171/E-MTAB-5171.additional.1.zip

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