Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: San-Huang-Yi-Shen Treats Diabetic Nephropathy

PROVIDER: PRJNA778921 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR16885140_1.fastq.gz	Fastqsanger.gz
	SRR16885140_2.fastq.gz	Fastqsanger.gz
	SRR16885141_1.fastq.gz	Fastqsanger.gz
	SRR16885141_2.fastq.gz	Fastqsanger.gz
	SRR16885142_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 36

Similar Datasets

San-Huang-Yi-Shen Treats Diabetic Nephropathy

Project description:San-Huang-Yi-Shen Treats Diabetic Nephropathy

| PRJEB48652 | ENA

LncRNAs expression profiles in renal tissues from patients with diabetic nephropathy

Project description:In order to more accurately and objectively clarify the biological role of lncRNAs in diabetic nephropathy, we detected their expression profiles in renal tissues from patients with diabetic nephropathy.

2022-11-24 | GSE218344 | GEO

Homo sapiens

Project description:Diabetic nephropathy

| PRJNA87073 | ENA

Glomerular Transcriptome Profiling Comparing DBA/2 and C57BL/6 mice

Project description:Comparing glomerular gene expression level between mice with different susceptibilities to diabetic nephropathy, DBA/2 (susceptible) and C57BL/6 (resistant) mice, respectively. The hypothesis is that differential expression of glomerular genes regulate susceptibility to diabetic nephropathy. The results show immune related genes. Thus, glomerular inflammation may increase susceptibility to diabetic nephropathy in mice. RNA isolated from kidney glomeruli of DBA/2 and C57BL/6 mice, with or without 4 weeks diabetes induced by streptozotocin.

2016-07-22 | E-GEOD-84663 | biostudies-arrayexpress

Human PBMCs: Healthy vs Diabetic nephropathy vs ESRD

Project description:Transcriptional profiling of human PBMCs comparing healthy controls, patients with diabetic nephropathy and patients with ESRD. PBMCs were analyzed as they mediate inflammatory injury. Goal was to determine effects of increasing severity of diabetic nephropathy on global PBMC gene expression. Microarray analysis of PBMCs taken from patients with varying degrees of diabetic nephropathy.

2020-12-01 | GSE142153 | GEO

Glomerular Transcriptome Profiling Comparing DBA/2 and C57BL/6 mice

2016-07-22 | GSE84663 | GEO

Expression data from kidney in type 2 diabetic db/db mice

Project description:Diabetic nephropathy(DN) is a common diabetic microvascular complication, the underlying mechanisms involved in DN remain to be elucidated. We used microarrays to explore the global profile of gene expression for better understanding the molecular mechanism of diabetic nephropathy in type 2 diabetic db/db mice.

2017-06-10 | GSE87359 | GEO

Single-Cell Profiling of Diabetic Nephropathy in a Murine Model Reveals Novel CellChat Signatures, Podocyte-to-Parietal Epithelial Cells Crosstalk

Project description:We used scRNA-seq to confirm the rich cellular interactions between podocytes and glomerular parietal epithelial cells in early diabetic nephropathy and to construct a global view of early diabetic nephropathy.

2024-10-31 | GSE216510 | GEO

Novel role of TrkC in diabetic nephropathy and cross-talk of TrkC with insulin-related signaling

Project description:Diabetic nephropathy is a major cause of end-stage renal disease. Kidney podocytes play a central role in the pathogenesis of diabetic nephropathy. With their intercellular contacts they assemble part of the kidney filter. Many molecular mechanisms of the pathogenesis of diabetic nephropathy are not elucidated and targeted therapies are lacking. Nephron-specific TrkCknockout (TrkC-KO) and TrkC overexpressing mice exhibit features of diabetic nephropathy such as enlarged glomeruli with mesangial proliferation, basement membrane thickening, albuminuria and podocyte loss when aging. Insulin-like growth factor 1 receptor (Igf1R)- associated gene expression was regulated in TrkC-KO mice glomeruli by qPCR. Phosphoproteins associated with insulin, erb-b2 receptor tyrosine kinase (Erbb) and Toll-like receptor signaling were enriched in lysates of podocytes treated with the TrkC ligand neurotrophin-3(Nt-3) in a mass spectrometry analysis. Activation of TrkC by Nt-3 resulted in phosphorylation of the Igf1R on activating tyrosine residues in podocytes. Our results identify TrkC to be a potentially targetable mediator of diabetic nephropathy.

2021-09-10 | PXD017960 | Pride

Effects of Irbesartan on Gene Expression Profiles in Kidney Tissues of Diabetic db/db Mice

Project description:Diabetic nephropathy(DN) is a common diabetic microvascular complication, Irbesartan is the first-line drug for clinical treatment of diabetic nephropathy, but its pharmacological mechanism and target are not yet fully clear. We used microarrays to explore the global profile of gene expression for better understanding the action mechanism of irbesartan in alleviating renal injuries of diabetic db/db mice

2024-05-29 | GSE178939 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data