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Chemical-based external stimulation reprograms human somatic cells into pluripotency

ABSTRACT: Chemical-based external stimulation reprograms human somatic cells into pluripotency

PROVIDER: PRJNA778967 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
	SRR14845740_1.fastq.gz	Fastqsanger.gz
	SRR14845740_2.fastq.gz	Fastqsanger.gz
	SRR14845741_1.fastq.gz	Fastqsanger.gz
	SRR14845741_2.fastq.gz	Fastqsanger.gz

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Chemical-based external stimulation reprograms human somatic cells into pluripotency (WGBS)

Project description:Chemical-based external stimulation reprograms human somatic cells into pluripotency (WGBS)

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Chemical-based external stimulation reprograms human somatic cells into pluripotency (WGBS)

Project description:Here, we report that chemical-based external stimulation reprograms human somatic cells to generate human induced pluripotent stem cells. Using transcriptome, chromatin accessibility and DNA methylome profiling, we identified the cells exhibited key features of embryonic stem cells in transcriptomic profiles, epigenetic status. In addition, we also analyzed the reprogramming process.

2022-02-08 | GSE178966 | GEO