Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mus musculus

ABSTRACT: Fusaproliferin attenuates inflammatory response in LPS-induced Raw264.7 macrophages

PROVIDER: PRJNA792467 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR17395244_1.fastq.gz	Fastqsanger.gz
	SRR17395244_2.fastq.gz	Fastqsanger.gz
	SRR17395245_1.fastq.gz	Fastqsanger.gz
	SRR17395245_2.fastq.gz	Fastqsanger.gz
	SRR17395246_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 18

Similar Datasets

Mus musculus

Project description:Proliferatin C attenuates inflammatory response in LPS-induced Raw264.7 macrophages

| PRJNA792469 | ENA

ATAC-seq profiling of Nfat5 KO and WT in Mus musculus macrophages

Project description:ATAC-seq profiling of Nfat5 KO and wild type macrophages derived from bone marrow (primary cells), treated or not with Lipopolysaccharide (LPS).

2021-06-09 | GSE111476 | GEO

Extracellular Vesicles Derived from Inflammatory Cardiomyocytes Mediate Macrophage Polarization and Alleviate Myocarditis via p38 MAPK Pathway

Project description:EVs derived from lipopolysaccharide （LPS）-stimulated cardiomyocytes （EVLPS） exhibit anti-inflammatory effects on macrophages and reduce cardiac inflammation in mice.To investigate gene expression changes induced by EVLPS treatment in inflammatory RAW264.7 using next-generation sequencing，we performed RNAseq.

2024-10-23 | GSE279575 | GEO

Gene expression profiles of RAW264.7 macrophage cells treated with Paeony root-derived compounds

Project description:Paeony root has long been used for its anti-inflammatory effects. In this study, the effects of albiflorin, paeoniflorin, and paeonol, compounds from paeony root, on gene expression profiles were examined in macrophages. The RAW264.7 macrophages were treated with LPS in the presence or absence of albiflorin, paeoniflorin, or paeonol. Global mRNA expression levels were detected by using an oligonucleotide microarray platform covering the mouse whole genome. Our results demonstrate that paeonol has extensive inhibitory effects on the regulation of inflammation-associated gene expression by LPS in macrophages. In addition, the predominant effect of paeonol among the tested compounds suggests that paeonol may be a major ingredient for the anti-inflammatory effect of paeony root. Keywords: RAW264.7; macrophage; inflammation; LPS; Paeony root components; dose response

2008-10-01 | GSE9632 | GEO

Effect of LPS on Mus musculus wild type and Tlr4 knockout brown adipocytes

Project description:The experiment was designed to determine the gene expression changes cultured brown adipocytes in response to the inflammatory stimulus of LPS treatment. Both wild type and TLR4 knockout cells were applied to enable assessment of the contribution of TLR4 to the response.

2024-03-21 | E-MTAB-12834 | biostudies-arrayexpress

A quantitative model for macrophage activation predicts tunable distance thresholds for propagation of inflammationes in response LPS stimulation

Project description:Label free analysis of the secretome of RAW264.7 murine macrophages in response to LPS stimulation.

2015-11-30 | PXD001905 | Pride

Mus musculus

Project description:Transcriptome profile in RAW264.7 cells in response to LPS stimulation

| PRJNA342311 | ENA

Stimulus-Response signaling dynamics characterize macrophage polarization states

Project description:RNAseq data from hMPDMs (HoxB4 myeloid progenitor derived macrophages), BMDMs (bone-marrow derived macrophages), and Raw264.7 cell line in unstimulated condition and 3 hours post LPS stimulation (lipopolysaccharide). Gene expression demonstrates similarities between hMPDMs and BMDMs supporting use of hMPDMs in this study of NFkB stimulus response signaling dynamics, whereas Raw264.7 cells are more distinct from BMDMs in terms of expression LPS-inducible genes.

2024-06-03 | GSE246566 | GEO

The Bromodomain and extraterminal (BET) inhibitor attenuates inflammatory response and cell migration in human microglia

Project description:We investigated the mechanisms underlying the anti-inflammatory and anti-migratory function and genes targeted by JQ1 in lipopolysaccharide (LPS)-activated human microglia HMC3 cells using RNA sequencing. The BET inhibitor JQ1 attenuates the LPS-induced inflammatory and migratory response. In addition, LPS-induced IRF1 was inhibited by JQ1, and IRF1 suppressed microglial migration by regulating inflammation and migration genes.

2021-04-28 | GSE155408 | GEO

Mus musculus

Project description:Igf1r deficiency attenuates acute inflammatory response and oxidative stress following bleomycin-induced lung injury

| PRJNA349061 | ENA