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RNASeq analysis of human ALDH- and ALDH+ DU145 xenografts in nu/nu mice upon radiotherapy treatment

ABSTRACT: RNASeq analysis of human ALDH- and ALDH+ DU145 xenografts in nu/nu mice upon radiotherapy treatment

PROVIDER: PRJNA798623 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR17661132_1.fastq.gz	Fastqsanger.gz
	SRR17661132_2.fastq.gz	Fastqsanger.gz
	SRR17661133_1.fastq.gz	Fastqsanger.gz
	SRR17661133_2.fastq.gz	Fastqsanger.gz
	SRR17661134_1.fastq.gz	Fastqsanger.gz

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RNASeq analysis of human ALDH- and ALDH+ DU145 xenografts in nu/nu mice upon radiotherapy treatment

Project description:Purpose: we aimed at identify and compare the transcriptional changes of ALDH- and ALDH+ DU145 xenografts upon radiotherapy treatment. Method: Xenografts were generated by injection of ALDH- and ALDH+ DU145 cells in male NMRI-Foxn1 nu/nu immune-deficient mice and subjected to fractionated irradiation to a final dose of 50 Gy. Tumors were excised and processed for total RNA extraction and RNAseq analysis.

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