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Transcriptomic analysis of donor matched primary human immature dendritic cells and monocyte-derived Langerhans cells

ABSTRACT: Transcriptomic analysis of donor matched primary human immature dendritic cells and monocyte-derived Langerhans cells

PROVIDER: PRJNA809703 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR18114779.fastq.gz	Fastqsanger.gz
	SRR18114780.fastq.gz	Fastqsanger.gz
	SRR18114781.fastq.gz	Fastqsanger.gz
	SRR18114782.fastq.gz	Fastqsanger.gz
	SRR18114783.fastq.gz	Fastqsanger.gz

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Transcriptomic analysis of donor matched primary human immature dendritic cells and monocyte-derived Langerhans cells

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Expression in donor monocyte derived cells

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Transcriptome modulation analysis of cytomegalovirus-infected immature monocyte-derived dendritic cells

Project description:Analysis of dendritic cells (DCs) at 6h and 48h after infection with cytomegalovirus (CMV) versus non infected. CMV tends to induce immunosuppression followed by lasting immunity. DCs appear to play a role in this effect. Results provide insights into CMV/DC interactions and suggest mechanisms for CMV-regulated early immune response. Keywords: gene expression array-based, count In the present study, immature monocyte-derived dendritic cells were generated from CMV neg healthy blood donors and infected or not with an endotheliotropic CMV strain. Gene expression modulation by the CMV infection was studied in a time course assay (non-infected - NI - vs 6h or 48h post-infection. Patient C has no 48h sample

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Expression in donor monocyte derived cells

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Trancriptomics of primary human monocytes, Langerhans cells (LC), and monocyte-derived Langerhans cells (moLC)

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