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Bead-Jet printing of high-density mesenchymal stem cell-laden Matrigel beads augments skeletal muscle and hair follicle regeneration [MSC]

ABSTRACT: Bead-Jet printing of high-density mesenchymal stem cell-laden Matrigel beads augments skeletal muscle and hair follicle regeneration [MSC]

PROVIDER: PRJNA810031 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR18128653_1.fastq.gz	Fastqsanger.gz
	SRR18128653_2.fastq.gz	Fastqsanger.gz
	SRR18128654_1.fastq.gz	Fastqsanger.gz
	SRR18128654_2.fastq.gz	Fastqsanger.gz
	SRR18128655_1.fastq.gz	Fastqsanger.gz

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Bead-Jet printing of high-density mesenchymal stem cell-laden Matrigel beads augments skeletal muscle and hair follicle regeneration [MSC]

Project description:We reported high-density encapsulation of MSCs in Matrigel beads, augmenting MSCs function, including increasing MSCs proliferation, migration, and extracellular vesicles (EVs) production via elevated PI3K-AKT pathway activity.

2022-02-28 | GSE197355 | GEO

Bead-Jet printing of high-density mesenchymal stem cell-laden Matrigel beads augments skeletal muscle and hair follicle regeneration [skeletal muscle]

Project description:We reported high-density encapsulation of MSCs in Matrigel beads, distributed in sparse pattern, augmenting mouse volumetric skeletal muscle tissue with reduced fibrosis.

2022-02-28 | GSE197356 | GEO

Bead-Jet printing of high-density mesenchymal stem cell-laden Matrigel beads augments skeletal muscle and hair follicle regeneration

Project description:Bead-Jet printing of high-density mesenchymal stem cell-laden Matrigel beads augments skeletal muscle and hair follicle regeneration

| PRJNA810023 | ENA

Mesenchymal stem cell-laden matrigel microspheres printing enables large skin wound regeneration

Project description:High cell density Matrigel beads (HDB) were printinto onto large skin wounds (10 mm and 15 mm). Compared with acellular beads printing, HDB group could achieve more efficient injury regeneration.

2022-10-12 | GSE214868 | GEO

Bead-Jet printing of high-density mesenchymal stem cell-laden Matrigel beads augments skeletal muscle and hair follicle regeneration [skeletal muscle]

Project description:Bead-Jet printing of high-density mesenchymal stem cell-laden Matrigel beads augments skeletal muscle and hair follicle regeneration [skeletal muscle]

| PRJNA810028 | ENA

Mesenchymal stem cell-laden matrigel microspheres printing enables large skin wound regeneration

Project description:Mesenchymal stem cell-laden matrigel microspheres printing enables large skin wound regeneration

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Bead-Jet printing of high-density mesenchymal stem cell-laden Matrigel beads augments skeletal muscle and hair follicle regeneration

Project description:This SuperSeries is composed of the SubSeries listed below.

2022-02-28 | GSE197358 | GEO

Comparison of small RNA Profiles of extracellular vesicles (EVs) derived from three mesenchymal stem cell-laden Matrigel composites

Project description:To investigate the difference of small RNA profiles of EVs derived from mesenchymal stem cell-laden Matrigel composites: high cell density beads (HDB) , low cell density beads (LDB) , and high cell density bulk ge (HDG)

2022-10-17 | GSE215294 | GEO

Bio-printing cell-laden Matrigel-agarose constructs.

Project description:3D printing of biological architectures that mimic the structural and functional features of in vivo tissues is of great interest in tissue engineering and the development of transplantable organ constructs. Printable bio-inks that are compatible with cellular activities play critical roles in the process of 3D bio-printing. Although a variety of hydrogels have been used as bio-inks for 3D bio-printing, they inherit poor mechanical properties and/or the lack of essential protein components that compromise their performance. Here, a hybrid Matrigel-agarose hydrogel system has been demonstrated that possesses both desired rheological properties for bio-printing and biocompatibility for long-term (11 days) cell culture. The agarose component in the hybrid hydrogel system enables the maintenance of 3D-printed structures, whereas Matrigel provides essential microenvironments for cell growth. When human intestinal epithelial HCT116 cells are encapsulated in the printed Matrigel-agarose constructs, high cell viability and proper cell spreading morphology are observed. Given that Matrigel is used extensively for 3D cell culturing, the developed 3D-printable Matrigel-agarose system will open a new way to construct Matrigel-based 3D constructs for cell culture and tissue engineering.

| S-EPMC5603305 | biostudies-literature

Comparison of small RNA Profiles of extracellular vesicles (EVs) derived from three mesenchymal stem cell-laden Matrigel composites

Project description:Comparison of small RNA Profiles of extracellular vesicles (EVs) derived from three mesenchymal stem cell-laden Matrigel composites

| PRJNA889722 | ENA

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