Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: ddRADseq for population genetics of the arctic seabird Pagophila eburnea

PROVIDER: PRJNA810851 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR18157100_1.fastq.gz	Fastqsanger.gz
	SRR18157100_2.fastq.gz	Fastqsanger.gz
	SRR18157101_1.fastq.gz	Fastqsanger.gz
	SRR18157101_2.fastq.gz	Fastqsanger.gz
	SRR18157102_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 342

Similar Datasets

The Genetic Prehistory of the New World Arctic

Project description:To carry out population genetics analyses of the Arctic gregion we carried out Illumina Bead-Array-based enotyping on 18 samples from Greenland.

2014-08-28 | GSE59546 | GEO

The Genetic Prehistory of the New World Arctic

Project description:To carry out population genetics analyses of the Arctic gregion we carried out Illumina Bead-Array-based enotyping on 18 samples from Greenland. 19 samples were analysed with the Illumina platform Human660W-Quad v1.0 Genotyping BeadChip and are described herein.

2014-08-28 | E-GEOD-59546 | biostudies-arrayexpress

Project description:ddRADseq for population genetics of the Nothern Chamois Rupicapra rupicapra

| PRJNA813419 | ENA

Project description:ddRADseq of Arctic charr (Salvelinus alpinus)

| PRJNA607173 | ENA

Project description:ddRADseq data for Arctic charr (Salvelinus alpinus)

| PRJNA1061680 | ENA

Project description:BAW Population Genetics

| PRJNA487086 | ENA

Project description:CFM population genetics

| PRJNA656320 | ENA

Project description:Cuckoo Population Genetics

| PRJNA614488 | ENA

Role of Microglial C5aR1 in the Arctic Alzheimer’s Disease Mouse Model

Project description:C5aR1, a receptor for the complement activation proinflammatory fragment, C5a, is primarily expressed on cells of the myeloid lineage, and to a lesser extent on endothelial cells and neurons in brain. Previous work demonstrated C5aR1 antagonist, PMX205, decreased amyloid pathology and suppressed cognitive deficits in Alzheimer Disease (AD) mouse models. In the Arctic AD mouse model, genetic deletion of C5aR1 prevented behavior deficits at 10 months. However, the molecular mechanisms of this protection has not been definitively demonstrated. To understand the role of microglial C5aR1 in the Arctic AD mouse model, we have taken advantage of the CX3CR1GFP and CCR2RFP reporter mice to distinguish microglia as GFP-positive and infiltrating monocytes as GFP and RFP positive, for subsequent transcriptome analysis on specifically sorted myeloid populations from wild type and AD mouse models. Immunohistochemical analysis of mice aged to 2, 5, 7 and 10 months showed no change in amyloid beta (Ab) deposition in the Arctic C5aR1 knockout (KO) mice relative to that seen in the Arctic mice. Of importance, no CCR2+ monocytes/macrophages were found near the plaques in the Arctic brain with or without C5aR1. RNA-seq analysis on microglia from these mice identified inflammation related genes as differentially expressed, with increased expression in the Arctic mice relative to wildtype and decreased expression in the Arctic/C5aR1KO relative to Arctic. In addition, phagosomal-lysosomal proteins and protein degradation pathways that were increased in the Arctic mice were further increased in the Arctic/C5aR1KO mice. These data are consistent with a microglial polarization state with restricted induction of inflammatory genes and enhancement of clearance pathways.

2017-10-10 | GSE93824 | GEO

Project description:Comparison of ddRADseq and EUChip60K SNP genotyping systems for population genetics and genomic selection in Eucalyptus dunnii (Maiden)

| PRJEB73817 | ENA

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data