Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Whole transcriptome sequencing of peripheral blood from opioid use disorder [RNA-seq]

ABSTRACT: Whole transcriptome sequencing of peripheral blood from opioid use disorder [RNA-seq]

PROVIDER: PRJNA813954 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR18268900_1.fastq.gz	Fastqsanger.gz
	SRR18268900_2.fastq.gz	Fastqsanger.gz
	SRR18268901_1.fastq.gz	Fastqsanger.gz
	SRR18268901_2.fastq.gz	Fastqsanger.gz
	SRR18268902_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 14

Similar Datasets

Whole transcriptome sequencing of peripheral blood from opioid use disorder

Project description:Whole transcriptome sequencing of peripheral blood from opioid use disorder

| PRJNA813839 | ENA

Whole transcriptome sequencing of peripheral blood from opioid use disorder [miRNA-seq]

Project description:Whole transcriptome sequencing of peripheral blood from opioid use disorder [miRNA-seq]

| PRJNA813953 | ENA

Effect of opioid use disorder on HIV latent reservoirs

Project description:Effect of opioid use disorder on HIV latent reservoirs

| PRJNA967476 | ENA

Whole transcriptome sequencing of peripheral blood from opioid use disorder [miRNA-seq]

Project description:7 male OUD patients and 7 male health controls with demographic and clinical data matched were enrolled in this study. rRNA removed library and small RNA library were constructed using peripheral blood RNA. RNA-seq was used to investigate the peripheral transcriptomic changes between the two groups.

2022-05-31 | GSE198122 | GEO

Whole transcriptome sequencing of peripheral blood from opioid use disorder [RNA-seq]

2022-05-31 | GSE198121 | GEO

Transcriptional responses of the human dorsal striatum in opioid use disorder implicates cell type-specifc programs

Project description:Gene expression profile at single cell level of striatal cells from the caudate nucleus and putamen in postmortem human brains of unaffected individuals or those with opioid use disorder.

2023-11-28 | GSE225158 | GEO

RNA-Seq of post mortem human central Amygdala samples in patients affected by opioid use disorder (OUD) vs. unaffected control samples

Project description:Differential expression analysis of human central Amygdala samples with a story of opioid use disorder (OUD) vs. unaffected control central Amygdala samples

2022-01-28 | GSE194368 | GEO

Transcriptional alterations in dorsolateral prefrontal cortex and nucleus accumbens implicate neuroinflammation and synaptic remodeling in opioid use disorder

Project description:Transcriptional alterations in dorsolateral prefrontal cortex and nucleus accumbens implicate neuroinflammation and synaptic remodeling in opioid use disorder. Transcriptomic profile of 20 control subjects and 20 OUD subjects in brain region DLPFC and NAC

2021-06-12 | GSE174409 | GEO

Profiling Neuronal Methylome and Hydroxymethylome of Opioid Use Disorder in the Human Orbitofrontal Cortex

Project description:Opioid use disorder (OUD) is influenced by genetic and environmental factors. While recent research suggests epigenetic disturbances in OUD, this is mostly limited to DNA methylation (5mC). DNA hydroxymethylation (5hmC) has been widely understudied. We conducted a multi-omics profiling of OUD in a male cohort, integrating neuronal-specific 5mC and 5hmC as well as gene expression profiles from human postmortem orbitofrontal cortex (OUD=12; non-OUD=26). Single locus methylomic analysis and co-methylation analysis showed a higher number of OUD-associated genes and gene networks for 5hmC compared to 5mC; these were enriched for GPCR, Wnt, neurogenesis, and opioid signaling. 5hmC marks also showed a higher correlation with gene expression patterns and enriched for GWAS of psychiatric traits. Drug interaction analysis revealed interactions with opioid-related drugs, some used as OUD treatments. Our multi-omics findings suggest an important role of 5hmC and reveal loci epigenetically dysregulated in OFC neurons of individuals with OUD.

2023-08-08 | GSE235818 | GEO

Whole transcriptome sequencing of peripheral blood from opioid use disorder

Project description:This SuperSeries is composed of the SubSeries listed below.

2022-05-31 | GSE198123 | GEO