Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma [epic_methyl]

ABSTRACT: UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma [epic_methyl]

PROVIDER: PRJNA815313 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma

Project description:UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma

| PRJNA815323 | ENA

UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma [CRISPR_screen]

Project description:UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma [CRISPR_screen]

| PRJNA976201 | ENA

UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma [shRNA]

Project description:UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma [shRNA]

| PRJNA862950 | ENA

UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma [RNA-seq]

Project description:UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma [RNA-seq]

| PRJNA814495 | ENA

UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma [RNA-seq]

Project description:RNA sequening was performed to understand the role of UHRF1 in regulation of gene expression in KRAS mutant lung cancer cell lines. Knock-down of both UHRF1 and KRAS leads to significant and overlapping changes in gene expression in both cell lines.

2023-05-15 | GSE198289 | GEO

UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma [epic_methyl]

Project description:Methylation array was performed to understand the role of UHRF1 in DNA methylation in KRAS mutant lung cancer cell lines. Knock-down of UHRF1 leads to significant changes in global DNA methylation in both cell lines.

2023-05-15 | GSE198446 | GEO

UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma [CRISPR_screen]

Project description:We performed a focused CRISPR in KRAS mutant lung cancer cells (A549) using a minipool sgRNA library targeting 80 lung cancer specific tumor suppressor genes and 12 control genes. This screen identified tumor suppressor genes regulated by Uhrf1 in KRAS mutant lung cancer.

2023-05-25 | GSE233401 | GEO

UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma [shRNA]

Project description:Using pooled shRNA libraries we performed a focused screen of 115 genes in 3D ex vivo cultures of primary murine lung tumor cells and 2D cultures of murine LKR10 cells. These screens identify Uhrf1 as gene selectively important for the 3D growth of primary lung cancer spheroids.

2023-05-15 | GSE209923 | GEO

Mediator Subunit 30 Directs Myc Oncogenesis

Project description:Mediator Subunit 30 Directs Myc Oncogenesis

| PRJNA899516 | ENA

UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma

Project description:This SuperSeries is composed of the SubSeries listed below.

2023-05-15 | GSE198450 | GEO