Project description:We measured steady-state transcript levels in 1) wild-type E. litoralis DSM 8509, 2) a nepR-ecfG deletion strain (ΔnepR-ecfG), 3) a phyR deletion strain (ΔphyR), 4) a lovK-lovR deletion strain (ΔlovKR), and 5) a gsrK-gsrP deletion strain (ΔgsrKΔgsrP) cultivated in constant white light or in constant dark conditions.
Project description:The hyperthermophilic archaeon Thermococcus litoralis strain NS-C, first isolated in 1985, has been a foundational organism for archaeal research in biocatalysis, DNA replication, metabolism, and the discovery of inteins. Here, we present the genome sequence of T. litoralis with a focus on the replication machinery and inteins.