Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gene expression profile of brains from Angptl2+/+ or Angptl2-/- mice

ABSTRACT: Gene expression profile of brains from Angptl2+/+ or Angptl2-/- mice

PROVIDER: PRJNA819873 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR18476872_1.fastq.gz	Fastqsanger.gz
	SRR18476872_2.fastq.gz	Fastqsanger.gz
	SRR18476873_1.fastq.gz	Fastqsanger.gz
	SRR18476873_2.fastq.gz	Fastqsanger.gz
	SRR18476874_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Gene expression profile of brains from Angptl2+/+ or Angptl2-/- mice

Project description:To identify the intracellular targets of ANGPTL2/MAG mediate signals that enhance oligodendrocyte differentiatiaon, brains from Angptl2+/+ or Angptl2-/- mice borned at Day 15 were obtained, followed by the extraction of total RNA and subjected to the RNA-sequencing.

2022-03-28 | GSE199393 | GEO

The clinical study to investigate between immune and gene-expression profile and clinical significance

Project description:Primary outcome(s): The clinical significance of immune and gene-expression profile in colorectal cancer

| 2659791 | ecrin-mdr-crc

Gene expression profile of juvenile R6/1 and N171-82Q brains

Project description:Gene expression profile of juvenile R6/1 and N171-82Q brains

| PRJNA420847 | ENA

Gene expression profile of IFNα transgenic mice

Project description:Gene expression profile of IFNα transgenic mice

| PRJNA509227 | ENA

Gene expression profile of HSCs and ANGPTL2 treated HSCs Transcriptomes

Project description:Gene expression profile of HSCs and ANGPTL2 treated HSCs Transcriptomes

| PRJNA715219 | ENA

Proteomic analysis of whole brains from Ndufs4-/- mice treated with doxycycline

Project description:Mice with mitochondrial complex I deficiency (Ndufs4-/-) suffer from severe energy impairment primarily affecting the brain and die at P55. A small molecule screen developed by our lab using cells harboring human mitochondrial disease mutations identified antibiotics targeting mitochondrial translation as potent inhibitors of cell death under nutrient stress conditions. Doxycycline, which was identified amongst these antibiotics, was administered in the diet of Ndufs4-/- mice after weaning at P21. Mice fed with doxycycline showed improved motor function and significantly increased lifespan relative to untreated Ndufs4-/- mice. In order to investigate the molecular changes promoted by doxycycline in the brains of these mice, Ndufs4-/- doxycycline treated (DOX), Ndufs4-/- untreated (KO), and Ndufs4+/+ (WT) control mice were sacrificed at P55 and their brains harvested. Proteomic analysis revealed doxycycline treatment largely prevented the neuroimmune and inflammatory profile identified in the Ndufs4-/- mice. These findings implicate a potentially causality of these proteins in the neuronal cell death ultimately leading to the observed brain pathology.

2021-09-09 | PXD022860 | Pride

Gene expression profile changes in brains of VSV-infected wild-type and Ifit2 knockout mice at 6 days after infection

Project description:Vesicular stomatitis virus replicates with marked effciency in Ifit2 knockout mouse brains late after infection (6 days after intranasal inoculation), compared to wt brains. Changes in gene expression, especially of interferon-stimulated genes, between late in infection (at 6 d p.i.) compared to early during infection (2 d p.i.) were examined in comparison to wild-type. Total RNA extracted from mouse brains of wt or Ifit2 knockout mice at 6 days after infection, compared to RNA from 2 days after infection.

2012-11-14 | E-GEOD-33678 | biostudies-arrayexpress

Gene expression data from zebrafish SHH medulloblastoma brains and normal brains.

Project description:Gene expression data from zebrafish SHH medulloblastoma brains and normal brains.

| PRJNA1015242 | ENA

Hemispheric lateralization of gene expression profile in stressed mice

Project description:Hemispheric lateralization of gene expression profile in stressed mice

| PRJNA470612 | ENA

Gene expression profile of HSCs and ANGPTL2 treated HSCs Transcriptomes

Project description:To identify the intracellular targets of ANGPTL2 that control HSC stemness, human cord blood CD34+ hematopoietic stem/progenitor cells (HSPCs) were stimulated with ANGPTL2 for 24 hr, followed by the extraction of total RNA and subjected to the RNA-sequencing.

2023-03-16 | GSE169107 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data