Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Single cell transcriptomic analysis of human axioloids

ABSTRACT: Single cell transcriptomic analysis of human axioloids

PROVIDER: PRJNA820750 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR18505652_1.fastq.gz	Fastqsanger.gz
	SRR18505652_2.fastq.gz	Fastqsanger.gz
	SRR18505653_1.fastq.gz	Fastqsanger.gz
	SRR18505653_2.fastq.gz	Fastqsanger.gz
	SRR18505654_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 24

Similar Datasets

Single-cell transcriptomic analysis of human hepatocellular carcinoma

Project description:Single-cell transcriptomic analysis of human hepatocellular carcinoma

| PRJNA609321 | ENA

Single Cell Transcriptomic Analysis of Human Pluripotent Stem Cell Chondrogenesis

Project description:Single Cell Transcriptomic Analysis of Human Pluripotent Stem Cell Chondrogenesis

| PRJNA674501 | ENA

A single cell transcriptomic analysis of human neocortical development

Project description:A single cell transcriptomic analysis of human neocortical development

| PRJNA545750 | ENA

A single cell transcriptomic analysis of human neocortical development

Project description:A single cell transcriptomic analysis of human neocortical development

| PRJNA545751 | ENA

Single cell transcriptomic analysis and Epigenomic profiling of human Axioloids

Project description:Single cell transcriptomic analysis and Epigenomic profiling of human Axioloids

| PRJNA820745 | ENA

Single cell transcriptomic analysis of human retina and RPE/choroid

Project description:Single cell transcriptomic analysis of human retina and RPE/choroid

| PRJNA841015 | ENA

Single-cell transcriptomic analysis of human germinal center B cells

Project description:Single-cell transcriptomic analysis of human germinal center B cells

| PRJNA587486 | ENA

Single-cell transcriptomic analysis of human skin organoids during folliculogenesis

Project description:Single-cell transcriptomic analysis of human skin organoids during folliculogenesis

| PRJNA966992 | ENA

Single Cell Transcriptomic Analysis of Human Pluripotent Stem Cell Chondrogenesis [scRNA-seq]

Project description:Single Cell Transcriptomic Analysis of Human Pluripotent Stem Cell Chondrogenesis [scRNA-seq]

| PRJNA673812 | ENA

A Single Cell Transcriptomic Analysis of Human Neocortical Development

Project description:<p>Defining the number, proportion, or lineage of distinct cell types in the developing human brain is an important goal of modern brain research. We produced single cell transcriptomic profiles for 40,000 cells at mid-gestation to define deep expression profiles corresponding to all known major cell types at this developmental period and compare this with bulk tissue profiles. We identified multiple transcription factors (TFs) and co-factors expressed in specific cell types, including multiple new cell-type-specific relationships, providing an unprecedented resource for understanding human neocortical development and evolution. This includes the first single-cell characterization of human subplate neurons and subtypes of developing glutamatergic and GABAergic neurons. We also used these data to deconvolute single cell regulatory networks that connect regulatory elements and transcriptional drivers to single cell gene expression programs in the developing CNS. We characterized major developmental trajectories that tie cell cycle progression with early cell fate decisions during early neurogenesis. Remarkably, we found that differentiation occurs on a transcriptomic continuum, so that differentiating cells not only express the few key TFs that drive cell fates, but express broad, mixed cell-type transcriptomes prior to telophase. Finally, we mapped neuropsychiatric disease genes to specific cell types, implicating dysregulation of specific cell types in ASD, ID, and epilepsy, as the mechanistic underpinnings of several neurodevelopmental disorders. Together these results provide an extensive catalog of cell types in human neocortex and extend our understanding of early cortical development, human brain evolution and the cellular basis of neuropsychiatric disease.</p>

| phs001836 | dbGaP

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data