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Effect of deletion of Irf3, Irf7 or Irf9 on gene expression in sgScd2 Th1 cells.

ABSTRACT: Effect of deletion of Irf3, Irf7 or Irf9 on gene expression in sgScd2 Th1 cells.

PROVIDER: PRJNA825571 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR18718488.fastq.gz	Fastqsanger.gz
	SRR18718489.fastq.gz	Fastqsanger.gz
	SRR18718490.fastq.gz	Fastqsanger.gz
	SRR18718491.fastq.gz	Fastqsanger.gz
	SRR18718492.fastq.gz	Fastqsanger.gz

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Effect of deletion of Irf3, Irf7 or Irf9 on gene expression in sgScd2 Th1 cells.

Project description:To investigate the role of the IRF family in the regulation of interferon stimulated genes, we conducted CRISPR/Cas9 mediated genome editing of Irf3, Irf7 or Irf9 in sgScd2 Th1 cells. We then performed gene expression profiling analysis using data obtained from RNA-seq of control, sgScd2, sgScd2/sgIrf3, sgScd2/sgIrf7 or sgScd2/sgIrf9 Th1 cells.

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