Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gene expression profile of Wild Type (WT) and P2x1 knockout (P2X1-KO) leukemia leukemia-initiating cells Transcriptomes

ABSTRACT: Gene expression profile of Wild Type (WT) and P2x1 knockout (P2X1-KO) leukemia leukemia-initiating cells Transcriptomes

PROVIDER: PRJNA826430 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR18741273_1.fastq.gz	Fastqsanger.gz
	SRR18741273_2.fastq.gz	Fastqsanger.gz
	SRR18741274_1.fastq.gz	Fastqsanger.gz
	SRR18741274_2.fastq.gz	Fastqsanger.gz
	SRR18741275_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 6

Similar Datasets

Gene expression profile of Wild Type (WT) and P2x7 knockout (P2X7-KO) leukemia leukemia-initiating cells Transcriptomes

Project description:Gene expression profile of Wild Type (WT) and P2x7 knockout (P2X7-KO) leukemia leukemia-initiating cells Transcriptomes

| PRJNA681910 | ENA

Next generating sequencing of primary murine WT and Gpr44 knockout leukemia-initiating cells in acute myeloid leukemia (AML) induced by MLL-AF9 oncogene

Project description:Knockout of GPR44 results in increased aggressiveness in AML leukemia-initiating cells, leading to worsened outcome in AML mice

2023-07-28 | GSE199629 | GEO

Gene expression profile of Wild Type (WT) and P2x7 knockout (P2X7-KO) leukemia leukemia-initiating cells Transcriptomes

Project description:To determine the underlying molecular mechanisms that control the homing and self-renewal activities of P2x7-null Mac-1+c-Kit+ LICs, WT and P2x7-null LICs were WT and P2x7-KO were sorted by flow cytometry, followed by the extraction of total RNA and subjected to the RNA-sequencing.

2023-11-30 | GSE162468 | GEO

Gene expression profile of Wild Type (WT) and P2x1 knockout (P2X1-KO) leukemia leukemia-initiating cells Transcriptomes

Project description:To determine the underlying molecular mechanisms that control the homing and self-renewal activities of P2x1-null Mac-1+c-Kit+ LICs, WT and P2x1-null LICs were WT and P2x1-KO were sorted by flow cytometry, followed by the extraction of total RNA and subjected to the RNA-sequencing.

2024-10-17 | GSE200724 | GEO

Sorting leukemia initiating cells from adult and neonatal leukemia

Project description:Sorting leukemia initiating cells from adult and neonatal leukemia

| PRJNA454711 | ENA

Quantitative Analysis of Wild Type(wt) and Setd2 knockout(ko) mESCs Transcriptomes [RNA-Seq]

Project description:Purpose: This study aimed at exploring the deregulated genes in setd2 knockout mESCs compared with wt, more particularly to find the mechanism controlled by setd2,which was required for endoderm differentiation. Methods: Setd2 wt and ko mESCs were generated by deep sequencing, using Illumina GAIIx. Using Avadis NGS (version:1.3) software to analyze the sequence reads that passed quality filter to acquire the expression level of all genes. qRT–PCR validation was performed usingSYBR Green assays. Results: Using an optimized data analysis workflow, we mapped about 80 million sequence reads per sample to the mouse genome (build mm9) and identified 17,827 transcripts in the sted2 wt and ko mESCs. About 2,516 genes were deregulated in setd2 ko mESCs, more than 10 genes were validated using qRT-PCR. Conclusions: Through RNA-seq,we noticed that a subset of genes that related to MAPK signaling pathways were down-regulated in ko mESCs. This provided a bridge to connect setd2 and mESCs endoderm differentiation. One wt and one ko mESCs were generated by deep sequencing, using Illumina GAIIx.

2014-10-14 | E-GEOD-54932 | biostudies-arrayexpress

HDAC8i/NAMPTi combination on the transcriptomes of leukemia initiating cells of AML patients

Project description:300 cell RNA-seq on FACS-sorted leukemia initiating cells (CD34+CD38-) from AML patients treated ex vivo with AR-42, KPT-9274 and AR-42/KPT-9274 combination

2021-02-10 | GSE161397 | GEO

Quantitative Analysis of Wild Type(wt) and Setd2 knockout(ko) mESCs Transcriptomes [RNA-Seq]

2014-10-14 | GSE54932 | GEO

Next generating sequencing of primary murine WT and Gpr44 knockout leukemia-initiating cells in acute myeloid leukemia (AML) induced by MLL-AF9 oncogene

Project description:Next generating sequencing of primary murine WT and Gpr44 knockout leukemia-initiating cells in acute myeloid leukemia (AML) induced by MLL-AF9 oncogene

| PRJNA820873 | ENA

Microarray-sequencing of WT and Jam3-null leukemia-initiating cells (LICs)

Project description:Microarray-sequencing of WT and Jam3-null leukemia-initiating cells (LICs)

| PRJNA430404 | ENA