Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Effect of habitat variation and host relatedness on Sceloporus cloacal microbiomes

PROVIDER: PRJNA827178 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR18793300_1.fastq.gz	Fastqsanger.gz
	SRR18793300_2.fastq.gz	Fastqsanger.gz
	SRR18793400_1.fastq.gz	Fastqsanger.gz
	SRR18793400_2.fastq.gz	Fastqsanger.gz
	SRR18793500_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 718

Similar Datasets

Project description:Host relatedness influences the composition of aphid microbiomes

| PRJNA573918 | ENA

Project description:Cloacal microbiomes in house finches

| PRJNA773380 | ENA

Project description:Demographic and seasonal variation in the cloacal microbiome of free-ranging striped plateau lizards, Sceloporus virgatus

| PRJNA813560 | ENA

Patient genetics is linked to chronic wound microbiome composition and healing

Project description:The clinical importance of microbiomes to the chronicity of wounds is widely appreciated, yet little is understood about patient-specific processes shaping wound microbiome composition. Here, a two-cohort microbiome-genome wide association study is presented through which patient genomic loci associated with chronic wound microbiome diversity were identified. Further investigation revealed that alternative TLN2 and ZNF521 genotypes explained significant inter-patient variation in relative abundance of two key pathogens, Pseudomonas aeruginosa and Staphylococcus epidermidis. Wound diversity was lowest in Pseudomonas aeruginosa infected wounds, and decreasing wound diversity had a significant negative linear relationship with healing rate. In addition to microbiome characteristics, age, diabetic status, and genetic ancestry all significantly influenced healing. Using structural equation modeling to identify common variance among SNPs, six loci were sufficient to explain 53% of variation in wound microbiome diversity, which was a 10% increase over traditional multiple regression. Focusing on TLN2, genotype at rs8031916 explained expression differences of alternative transcripts that differ in inclusion of important focal adhesion binding domains. Such differences are hypothesized to relate to wound microbiomes and healing through effects on bacterial exploitation of focal adhesions and/or cellular migration. Related, other associated loci were functionally enriched, often with roles in cytoskeletal dynamics. This study, being the first to identify patient genetic determinants for wound microbiomes and healing, implicates genetic variation determining cellular adhesion phenotypes as important drivers of infection type. The identification of predictive biomarkers for chronic wound microbiomes may serve as risk factors and guide treatment by informing patient-specific tendencies of infection.

2020-04-25 | GSE149314 | GEO

A resilient mutualistic interaction between cucumber mosaic virus and its natural host Arabidopsis halleri to adapt to an environmental change

Project description:A pseudometallophyte Arabidopsis halleri is frequently found to be infected with cucumber mosaic virus (CMV) in its natural habitat. The purpose of this study is to elucidate the effect of CMV infection on its natural hosts. The CMV(Ho) strain isolated from A. halleri was inoculated into clonal A. halleri plants that were obtained from runners of mother plants, and the pathosystem consisting of CMV(Ho) and its natural host A. halleri was established.In low heavy metal environment, the CMV(Ho) infection caused growth retardation in the above-ground part (stems and leaves) of host plants, and thereby conferred strong drought tolerance on host plants. On the other hand, in high heavy metal environment, which simulates a natural habitat for A halleri, the CMV(Ho) infection did not cause any symptoms to host plants and conferred mild drought tolerance. And the result of transcriptome analysis suggests that CMV(Ho) is recognized as a symbiont rather than a pathogen by its host plant. These results indicate a resilient mutualistic interaction between CMV(Ho) and its natural host A. halleri to adapt to an environmental change.

2022-03-05 | GSE197739 | GEO

Project description:Cloacal microbiomes of Passerine birds from Papua New Guinea

| PRJNA673580 | ENA

Project description:Cloacal microbiomes of Passerine birds from Papua New Guinea_2018

| PRJNA673591 | ENA

Project description:Cloacal microbiomes of Passerine birds from Papua New Guinea_2019

| PRJNA673602 | ENA

Lemur fecal samples

Project description:Lemur gut microeukaryotic community variation is not associated with host phylogeny, diet, or habitat

| PRJNA913825 | ENA

Brent Goose Gut Microbiomes

Project description:Habitat Selection Effects on Brent Goose Gut Microbiomes

| PRJEB29443 | ENA

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data