Project description:we performed a comparative proteomics analysis of Korla fragrant pear after inoculation with Alternaria sp., at 0h, 24h, 72h, 120 h using iTRAQ-based quantitative proteomic technique. This study aimed to investigate the protein species expression profiles in response to Alternaria sp., infection, explore the potential molecular mechanisms of Korla fragrant pear response against Alternaria sp., and further obtain a comprehensive understanding of Korla fragrant pear-Alternaria sp interactions. The finding may provide novel clues to Korla fragrant pear resistance to Alternaria sp., and may lay the foundation for an in-depth understanding of the interaction between Korla fragrant pear and Alternaria sp., at the proteome level.
Project description:In the present study, we used the single prolonged stress (SPS) model to mimic posttraumatic stress disorder. High-throughput sequencing were utilized to analyze differentially expressed genes (DEGs) in the hippocampus of control and SPS rats. RNA-seq analysis revealed 230 significantly DEGs between the control and SPS groups.
