Project description:ChIP-chip analyses of lysine-9 trimethylated histone H3 in clr3-CDx2 and wild type cells. Chromodomain-mediated HDAC loading sustains self-templated propagation of extended heterochromatin domain.
Project description:ChIP-chip analyses of pulse-expressed H3-T7 in clr3-CDx2 and wild type cells Chromodomain-mediated HDAC loading suppresses histone turnover at self-templated heterochromatin domain. Chromodomain-mediated loading targets Clr3-CDx2 to heterochromatin domains.