Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

EHF and CDX1 co-operate to drive extensive transcriptional reprogramming and chromatin remodelling in CRC cells [RNA-seq]

ABSTRACT: EHF and CDX1 co-operate to drive extensive transcriptional reprogramming and chromatin remodelling in CRC cells [RNA-seq]

PROVIDER: PRJNA834148 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

EHF and CDX1 co-operate to drive extensive transcriptional reprogramming and chromatin remodelling in CRC cells [ATAC-seq]

Project description:EHF and CDX1 co-operate to drive differentation of CRC cells. To identify the change in chromatin remodelling induced by these transcription factors, EHF and CDX1 were stably re-expressed in poorly differentiated HCT116 CRC cells and ATAC-seq analysis performed.

2022-11-02 | GSE202072 | GEO

EHF and CDX1 co-operate to drive extensive transcriptional reprogramming and chromatin remodelling in CRC cells [RNA-seq]

Project description:EHF and CDX1 co-operate to drive differentation of CRC cells. To identify the transcriptional changes induced by these transcription factors, EHF and CDX1 were stably re-expressed in poorly differentiated HCT116 CRC cells and RNA sequencing analysis performed.

2022-11-02 | GSE202073 | GEO

EHF and CDX1 co-operate to drive extensive transcriptional reprogramming and chromatin remodelling in CRC cells

Project description:EHF and CDX1 co-operate to drive extensive transcriptional reprogramming and chromatin remodelling in CRC cells

| PRJNA834145 | ENA

EHF and CDX1 co-operate to drive extensive transcriptional reprogramming and chromatin remodelling in CRC cells [ATAC-seq]

Project description:EHF and CDX1 co-operate to drive extensive transcriptional reprogramming and chromatin remodelling in CRC cells [ATAC-seq]

| PRJNA834149 | ENA

EHF and CDX1 co-operate to drive extensive transcriptional reprogramming and chromatin remodelling in CRC cells

Project description:This SuperSeries is composed of the SubSeries listed below.

2022-11-02 | GSE202074 | GEO

EHF is an essential regulator of mammary alveolar lineage differentiation and putative suppressor of breast tumorigenesis

Project description:The Ets homologous factor (Ehf) is highly expressed in the mammary gland in pregnancy and lactation. Mothers with Ehf deletion fail to lactate due to impaired lobuloalveolar development. ATACseq profiling of luminal mammary epithelial cells at late pregnancy (18.5dP) demonstrated that loss of Ehf results in significant chromatin remodelling.

2024-04-28 | GSE260878 | GEO

Transcription profiling of human colorectal cancer cell lines transfected with homeobox gene CDX1 cDNA to identfiy downstream targets

Project description:This study is to identify downstream targets of homeobox gene CDX1. The study assayed the expression of 2 pairs of stably transfected colorectal cancer cell lines: The CDX1 nonexpressing CRC cell line HCT116 was stably transfected with either CDX1 cDNA in the pRC/CMV expression vector (HCT116-CDX1) or with vector control (HCT116-Vec). The CDX1-expressing CRC cell line LS174T was similarly transfected with either a pSilencer vector containing a short sequence of CDX1 siRNA (LS174T-siRNA) , or a pSilencer vector containing a scrambled siRNA sequence as a control (LS174T-Vec). Experiment Overall Design: 2 pairs of colorectal cancer cell lines were used for comparison

2009-01-23 | E-GEOD-14380 | biostudies-arrayexpress

Identification of genes differentially expressed between control and EHF siRNA transfected HCT116 cells

Project description:we found that EHF allowed colon tumor cells to escape p53-mediated apoptosis.We performed microarray analysis to find the target genes of EHF. A colorecal cancer cell line HCT116 was transfected with an siRNA targeting EHF or negative control.

2010-07-29 | E-GEOD-22265 | biostudies-arrayexpress

Expression data from siRNA knockdown of Ehf in primary human corneal epithelial cells

Project description:Ehf is a transcriptional regulator that is highly expressed and enriched in corneal epithelium. To gain insights into the role of Ehf in the corneal epithelium, we performed siRNA knockdown of Ehf in primary human corneal epithelial cells. Primary human corneal epithelial cells were transfected with siEhf or si controls, plated, and harvested at 72 hr.

2013-01-01 | E-GEOD-43157 | biostudies-arrayexpress

Gastrointestinal differentiation marker Cytokeratin 20 is regulated by homeobox gene CDX1

2009-01-13 | GSE14380 | GEO