Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

A hPSC system for characterizing MUC5B-expressing airway epithelia

ABSTRACT: A hPSC system for characterizing MUC5B-expressing airway epithelia

PROVIDER: PRJNA835444 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR19096150.fastq.gz	Fastqsanger.gz

Items per page:

1 - 1 of 1

Similar Datasets

A hPSC system for characterizing MUC5B-expressing airway epithelia

Project description:scRNA-seq of air-liquid interface airway epithelial cultures derived from a human fluorescent reporter hPSC line labeling MUC5B-expressing cells

2023-05-04 | GSE202313 | GEO

The MUC5B IPF risk variant promotes a distal airway secretory phenotype and loss of alveolar markers

Project description:The dominant risk factor for the development of idiopathic pulmonary fibrosis (IPF) is a common variant in the promoter region of the airway mucin MUC5B, variant rs35705950. The MUC5B promoter variant enhances MUC5B expression in the terminal respiratory bronchiole, where it is normally absent. We pursued a spatial gene expression approach to understand how the MUC5B variant influences IPF in age-matched unaffected and IPF lung tissue specimens.

2024-07-29 | GSE267521 | GEO

Expression data from human airway epithelia exposed to IL13

Project description:IL13 exposure results in a distinct gene expression profile in human airway epithelia. We investigated whether this expression profile can be used to identify compounds able to block goblet cell metaplasia We used microarrays to determine transcriptional changes in cultures of primary human airway epithelia grown at the air-liquid interface after exposure to 20 ng/mL recombinant human IL13

2017-11-14 | GSE106812 | GEO

Repair of airway epithelia requires metabolic rewiring towards fatty acid oxidation

Project description:Repair of airway epithelia requires metabolic rewiring towards fatty acid oxidation

2023-01-31 | GSE218663 | GEO

Single cell RNA sequencing of healthy human airway epithelia

Project description:The goal of this study was to compare cell composition and gene expression of different cell types in healthy primary human airway epithelia cultured at the air-liquid interface

2021-10-02 | GSE185048 | GEO

Single-cell RNA sequencing of human airway epithelia infected with measles virus (MeV)

Project description:The goal of this study was to compare cell composition, gene expression, and infectivity of different cell types in human airway epithelia following exposure to measles virus. Samples included control epithelia exposed to a mock infection and measles-virus-exposed epithelia that were sorted according to detection of green fluorescent protein (GFP) prior to library preparation and sequencing.

2021-08-06 | GSE168775 | GEO

Pulmonary fibrosis distal airway epithelia are dynamically and structurally dysfunctional

Project description:To identify genes regulating the jamming transition in healthy distal airway epithelia compared to the dysregulated state in idiopathic pulmonary fibrosis epithelia (IPF) we analyzed RNA from three (3) healthy and four (4) IPF patient cells grown at air-liquid-interface (ALI). This bulk analysis of 3 timepointes (days 4, 8, and 14 of ALI) spanning the jamming transition revealed an enrichment for ERBB- and YAP-related genes.

2021-07-01 | GSE176001 | GEO

RNA sequencing of healthy human airway epithelia with IL-13 treatment time course

Project description:The goal of this study was to examine changes to gene expression induced by IL-13 treatment of air-liquid interface cultures of healthy primary human airway epithelia over time.

2023-08-16 | GSE240741 | GEO

Secretory Cells Dominate Airway CFTR Expression and Function in Human Airway Superficial Epithelia

Project description:Secretory Cells Dominate Airway CFTR Expression and Function in Human Airway Superficial Epithelia

| PRJNA673903 | ENA

Expression data from human airway epithelia exposed to IL13

Project description:Expression data from human airway epithelia exposed to IL13

| PRJNA418124 | ENA