Project description:We obtained comprehensive protein profiles from testes of Tibetan sheep at three developmental stages (including pre-puberty, post-puberty and adulthood) using data-independent acquisition-based proteomic strategy to quantitatively identify the differentially abundant proteins (DAPs) associated with testicular development and function and to unravel the molecular basis of spermatogenesis in Tibetan sheep.
Project description:The heart plays a crucial role in the adaptation of Tibetan sheep to hypoxia. In the present study, we utilized proteomic technologies to comprehensively analyze and identify the proteins, pathways, and Gene Ontology (GO) terms associated with hypoxic adaptation in Tibetan sheep at three different altitudes (2500m, 3500m, and 4500m).