Project description:Activation of the Sonic hedgehog (Shh) signaling pathway due to Patched 1 (PTCH1) mutation is a key event in sporadic and familial basal cell carcinoma (BCC) development. To find out the specific pathway for therapeutic intervention, we developed a mouse BCC model by skin specific Ptch1 inactivation, and sought to identify novel Shh targets. We used microarrays to identify up-regulated genes in mouse BCC. We used microarrays to identify down-regulated genes in mouse BCC cell line by cyclopamine.

2018-01-15 | GSE20065 | GEO

Single-cell ATAC-Seq (scATAC-Seq) of mouse basal cell carcinoma (BCC) immune cells.

Project description:Single-cell ATAC-Seq (scATAC-Seq) of mouse basal cell carcinoma (BCC) immune cells.

| PRJNA842575 | ENA

Single-cell ATAC-Seq and RNa-seq of human and mouse basal cell carcinoma (BCC)

Project description:Single-cell ATAC-Seq and RNa-seq of human and mouse basal cell carcinoma (BCC)

| PRJNA772786 | ENA

Single-cell ATAC-Seq (scATAC-Seq) of mouse basal cell carcinoma (BCC) immune cells.

Project description:We used scATAC-Seq to examine BCC immune cell heterogeneity.

2023-03-29 | GSE204863 | GEO

Murine BCC Cells: dio3 interfered vs control

Project description:MicroRNA expression profiling of mouse basal cell carcinoma (BCC) cells comparing BCC cells transfected with a stealth for dio3 transcript or control stealth-RNA.

2016-02-24 | GSE78265 | GEO

Murine BCC Cells: dio3 interfered vs control

Project description:MicroRNA expression profiling of mouse basal cell carcinoma (BCC) cells comparing BCC cells transfected with a stealth for dio3 transcript or control stealth-RNA. Two-condition experiment, Stealth-D3 vs Stealth-CTR cells. Biological replicates: 3 Stealth-D3 and 3 Stealth-CTR, independently grown and harvested. Single RNA were pooled. One replicate per array.

2016-02-24 | E-GEOD-78265 | biostudies-arrayexpress

scRNA-Seq of Mouse Trachea Basal Cells

Project description:scRNA-Seq of Mouse Trachea Basal Cells

| PRJNA553671 | ENA