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Single cell gene expression profile of hPSC-derived nephric duct spheroids (day 7) and collecting duct organoiods (day 18)

ABSTRACT: Single cell gene expression profile of hPSC-derived nephric duct spheroids (day 7) and collecting duct organoiods (day 18)

PROVIDER: PRJNA849510 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR19661811_1.fastq.gz	Fastqsanger.gz
	SRR19661811_2.fastq.gz	Fastqsanger.gz
	SRR19661812_1.fastq.gz	Fastqsanger.gz
	SRR19661812_2.fastq.gz	Fastqsanger.gz
	SRR19661813_1.fastq.gz	Fastqsanger.gz

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Single cell gene expression profile of hPSC-derived nephric duct spheroids (day 7) and collecting duct organoiods (day 18)

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Project description:Transcriptional profiling of new born mouse kidney collecting duct (CD) cells comparing the infuence of gestational high salt stress on gene expression remolding of BdkrB2 receptor knockout CD cells with that of BdkrB2 receptor wild type CD cells. The BdkrB2 receptor has been shown to be playing a role in renal vascular tone, kidney secretion and reabsorption function, normal kidney development, while impaired BdkrB2 receptor in kidney shown being associated with renal agenesis and renal dysplasia. Goal was to determine the effects of BdkrB2 receptor knockout together with gestational high salt stress on collecting duct gene expression pattern.

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