Project description:Mice were treated with DSS and anti-PD1 to induce colitis, comparable to patients suffering from ICI-induced immune-related adverse events. ECP showed beneficial effects in patients. Mice were transplanted with ECP-tretaed cells as treatment and RNA was extracted from colitis tissue to anravel the mechanisms causing the reduction of colitis severity.

2024-11-27 | GSE207823 | GEO

Comparative cardiac transcriptomics of immune checkpoint inhibitor induced myocarditis

Project description:Comparative cardiac transcriptomics of immune checkpoint inhibitor induced myocarditis

| PRJEB37155 | ENA

Colitis associated with immune checkpoint inhibitors

Project description:Colitis associated with immune checkpoint inhibitors

| PRJNA849977 | ENA

Comparative cardiac transcriptomics of immune checkpoint inhibitor induced myocarditis

Project description:Immune checkpoint inhibitors (ICIs) are improving cancer treatments strikingly. The raising use leads to the augmented occurrence of immune related events. Myocarditis is a rare, but severe form of these adverse events. Nine patients with proven ICI induced myocarditis were subjected to myocardial biopsy. The tissue was used for RNA-seq analyses.

2020-11-01 | E-MTAB-8867 | biostudies-arrayexpress

Colitis associated with immune checkpoint inhibitors [tissue_nuclei]

Project description:Colitis associated with immune checkpoint inhibitors [tissue_nuclei]

| PRJNA849980 | ENA

Colitis associated with immune checkpoint inhibitors [blood_cells]

Project description:Colitis associated with immune checkpoint inhibitors [blood_cells]

| PRJNA849982 | ENA