Project description:Gene expression profiling of immortalized human mesenchymal stem cells with hTERT/E6/E7 transfected MSCs. hTERT may change gene expression in MSCs. Goal was to determine the gene expressions of immortalized MSCs.
Project description:Transcriptional profiling of human mesenchymal stem cells comparing normoxic MSCs cells with hypoxic MSCs cells. Hypoxia may inhibit senescence of MSCs during expansion. Goal was to determine the effects of hypoxia on global MSCs gene expression.
Project description:ZFPM2-AS1 can promote the proliferation, migration and invasion of tumor cells, but its mechanism is still unclear.To investigate the molecular mechanism of malignant progression of breast phyllode tumors, we knocked down the expression of ZFPM2-AS1 in malignant phyllode tumor cells, and detected the genes regulated by ZFPM2-AS1 by RNAseq.