Project description:Copy number loss of AKTIP gene is frequently observed in breast cancer particularly luminal breast cancer. To determine the alterations in transcriptome upon AKTIP loss in luminal breast cancer cell line MCF7 and triple negative breast cancer cell line SKBR3, RNAseq of cells transfected with AKTIP siRNA was performed.

2022-08-19 | GSE209693 | GEO

Effect of depletion of TRIM25 and inhibition of p300 on gene expression in breast cancer cells

Project description:Effect of depletion of TRIM25 and inhibition of p300 on gene expression in breast cancer cells

| PRJNA888377 | ENA

Effect of depletion of YAP1 on gene expression in triple negative breast cancer

Project description:Effect of depletion of YAP1 on gene expression in triple negative breast cancer

| PRJNA833398 | ENA

NAT10 depletion suppresses fatty acid metabolism in MCF7 breast cancer cells

Project description:NAT10 depletion suppresses fatty acid metabolism in MCF7 breast cancer cells

| PRJNA863634 | ENA

Mufudza2012 - Estrogen effect on the dynamics of breast cancer

Project description:Mufudza2012 - Estrogen effect on the dynamics of breast cancer This deterministic model shows the dynamics of breast cancer with immune response. The effects of estrogen are incorporated to study its effects as a risk factor for the disease. This model is described in the article: Assessing the effects of estrogen on the dynamics of breast cancer. Mufudza C, Sorofa W, Chiyaka ET. Comput Math Methods Med 2012; 2012: 473572 Abstract: Worldwide, breast cancer has become the second most common cancer in women. The disease has currently been named the most deadly cancer in women but little is known on what causes the disease. We present the effects of estrogen as a risk factor on the dynamics of breast cancer. We develop a deterministic mathematical model showing general dynamics of breast cancer with immune response. This is a four-population model that includes tumor cells, host cells, immune cells, and estrogen. The effects of estrogen are then incorporated in the model. The results show that the presence of extra estrogen increases the risk of developing breast cancer. This model is hosted on BioModels Database and identified by: BIOMD0000000642. To cite BioModels Database, please use: BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information.

2024-09-02 | BIOMD0000000642 | BioModels

Effect of SCN5A depletion on gene expression in xenograft tumours of MDA-MB-231 breast cancer cells

Project description:Effect of SCN5A depletion on gene expression in xenograft tumours of MDA-MB-231 breast cancer cells

| PRJNA950459 | ENA

Effect of cisplatin in depletion MAGEA6 expression of esophageal cancer cells

Project description:Effect of cisplatin in depletion MAGEA6 expression of esophageal cancer cells

| PRJNA956915 | ENA