Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Transcriptome of Ganoderma lucidum

PROVIDER: PRJNA865720 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR21137466_1.fastq.gz	Fastqsanger.gz
	SRR21137466_2.fastq.gz	Fastqsanger.gz
	SRR21137467_1.fastq.gz	Fastqsanger.gz
	SRR21137467_2.fastq.gz	Fastqsanger.gz
	SRR21137468_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 18

Similar Datasets

Ganoderma lucidum

Project description:Ganoderma lucidum Transcriptome

| PRJNA736534 | ENA

Project description:Ganoderma lucidum transcriptome

| PRJNA798550 | ENA

Project description:Ganoderma lucidum transcriptome

| PRJNA1016094 | ENA

Project description:Ganoderma lucidum transcriptome sequencing

| PRJNA1107921 | ENA

A randomized, double-blind, placebo-controlled trial for the efficacy and safety of Ganoderma lucidum spore powder in the adjuvant therapy of postoperative patients with colorectal cancer

Project description:Interventions: Experimental group:Ganoderma lucidum spore powder;Control group:Placebo Primary outcome(s): Chemotherapy tolerance improvement Study Design: Single arm

| 2688644 | ecrin-mdr-crc

Ganoderma lucidum

Project description:Ganoderma Lucidum transcriptome sequence reads

| PRJNA559154 | ENA

Hydrogen sulfide, a novel small molecule signalling agent, participates in GAs biosynthesis under heat stress and the regulation of multiple signaling pathway genes in Ganoderma lucidum

Project description:As one of the most important environmental factors, heat stress (HS) has been found to affect various biological activities of organisms such as growth, signal transmission, primary metabolism and secondary metabolism. Ganoderma lucidum has become a potential model system for evaluating how environmental factors regulate the secondary metabolism of basidiomycetes. Previous research showed that HS can induce the biosynthesis of ganoderic acids (GAs). In this study, we found the existence of hydrogen sulfide in Ganoderma lucidum; moreover, HS increased GAs biosynthesis and could affect the hydrogen sulfide content. We found that sodium hydrosulfide (NaHS), an exogenous donor of hydrogen sulfide, could revert the increased GAs biosynthesis elicited by HS. This result indicated that an increased content of hydrogen sulfide, within limits, was associated with HS-induced GAs biosynthesis. Our results further showed that the GAs content was increased in CBS-silenced strains and could be reverted to WT strain levels by the addition of NaHS. Transcriptomic analyses indicated that that H2S can affect various intracellular signal pathways and physiological processes in G. lucidum. Further studies showed that H2S could affect the intracellular calcium concentration and thus regulate the biosynthesis of GAs. This study demonstrated that hydrogen sulfide is involved in the regulation of secondary metabolic processes induced by heat stress in filamentous fungi.

2021-10-12 | GSE121270 | GEO

Ganoderma lucidum

Project description:Ganoderma lucidum Metagenome

| PRJNA389612 | ENA

Adenosine-rich extract of Ganoderma lucidum: a safe and effective lipid-lowering substance via regulating expression and modulation of PPAR signaling pathway

Project description:Ganoderma lucidum is a traditional Chinese medicine with a variety of active compounds and possessing adequate lipid-lowering and anti-atherosclerotic effects. However, its main active components and potential mechanisms still remain unclear. Here, we evaluated the anti-hyperlipidemic effect of the adenosine extract from Ganoderma lucidum (AEGL) in high-fat-diet (HFD)-induced hyperlipidemic ApoE-/- mice and explored the underlying biological mechanism by multi-omics analysis. Treatment with AEGL for 8 weeks significantly decreased the serum levels of total cholesterol (TC), triglyceride (TG), and low-density lipoprotein cholesterol (LDL-c) by 45.59%, 41.22%, and 39.02%, respectively, as well as reduced liver TC and TG by 44.15% and 76.23%, compared with the HFD-only group. We also observed significant amelioration of hepatic steatosis without liver and kidney damage after AEGL treatment. Regulating the expression and acetylation/crotonylation of proteins involved in the PPAR signaling pathway may be one of the potential mechanisms involved in the observed lipid-lowering effects of AEGL.

2023-03-11 | PXD036478 | Pride

Ganoderma lucidum

Project description:Ganoderma lucidum Transcriptome or Gene expression

| PRJNA613866 | ENA