Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mus musculus strain:FAH-/- (deltaExon5)

ABSTRACT: Multiomics characterization of mouse hepatoblastoma identifies yes-associated protein 1 target genes

PROVIDER: PRJNA869853 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR21281755.fastq.gz	Fastqsanger.gz
	SRR21281755_1.fastq.gz	Fastqsanger.gz
	SRR21281755_2.fastq.gz	Fastqsanger.gz
	SRR21281756.fastq.gz	Fastqsanger.gz
	SRR21281756_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 33

Similar Datasets

Human Yes Associated Protein (hYAP) expressing mouse liver

Project description:Human Yes Associated Protein (hYAP) expressing mouse liver

| PRJNA384350 | ENA

Mus musculus

Project description:Role of Yes-Associated Protein 1 (YAP1) in rhabdomyosarcoma

| PRJNA205068 | ENA

Project description:Yes-associated protein in hepatocytes protects against early alcohol-associated liver disease

| PRJNA1103676 | ENA

Mus musculus

Project description:Human Yes Associated Protein (hYAP) expressing mouse liver (set 2)

| PRJNA384356 | ENA

Mus musculus

Project description:Human Yes Associated Protein (hYAP) expressing mouse liver (set 1)

| PRJNA384357 | ENA

Nassar2022 - Microbiome target gene NER model

Project description:Microbiome target gene model is a Named Entity Recognition (NER) model that identifies and annotates microbiome target genes, phylogenetic marker genes or hypervariable regions in texts. This is the final model version used to annotate metagenomics publications in Europe PMC and enrich metagenomics studies in MGnify with target genes metadata from literature. For more information, please refer to the following blogs: http://blog.europepmc.org/2020/11/europe-pmc-publications-metagenomics-annotations.html https://www.ebi.ac.uk/about/news/service-news/enriched-metadata-fields-mgnify-based-text-mining-associated-publications

2022-02-21 | MODEL2202170005 | BioModels

RNA sequencing of pancreatic adenocarcinoma (PDAC) xenograft samples

Project description:Pancreatic adenocarcinoma (PDAC) is one of the most lethal human malignancies and a major health problem. Patient-derived xenografts (PDX) are appearing as a prime approach for preclinical studies despite being insufficiently characterized as a model of the human disease and its diversity. We generated subcutaneous PDX from PDAC samples obtained either surgically or using diagnostic biopsies (endoscopic ultrasound guided fine needle aspirate). The extensive multiomics characterization of the xenografts demonstrated that PDX is a suitable model for preclinical studies, representing the diversity of the primary cancers. this dataset, describe the RNA sequencing data used in the multiomics study.

2017-12-12 | E-MTAB-5039 | biostudies-arrayexpress

YAP orchestrates heterotypic endothelial cell communication via HGF/c-MET signaling in liver tumorigenesis

Project description:Disturbance of heterologous cell communication is associated with a structural reorganization of the vascular niche, a process called capillarization, which is already initiated in early stages of liver tumor development. In this study, the molecular characterization of endothelial cell (EC) subpopulations from healthy livers and yes-associated protein (Yap)-induced liver tumors revealed a dynamic crosstalk between liver sinusoidal endothelial cells (LSECs) and capillary endothelial cells (CECs). Initial paracrine stimuli from parenchymal cells include the Yap/Tead4 target gene osteopontin (Opn), which promotes CECs expansion through the induction of c-Met and sensitization towards LSEC-derived hepatocyte growth factor (Hgf). In addition, Yap/Tead4-induced C-C motif chemokine ligand 2 (Ccl2) recruits bone-marrow-derived macrophages (BMDMs) with an unpolarized phenotype (M0) to the perivascular space of expanding CECs.

2020-09-15 | GSE128046 | GEO

Liver macrophages in YapS127A and wildtype livers

2020-09-15 | GSE128045 | GEO

YAP orchestrates heterotypic endothelial cell communication via HGF/c-MET signaling in liver tumorigenesis

2020-09-15 | GSE128044 | GEO