Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Distinct Microbiomes of Tongue Coating and Gut in Type 2 Diabetes With Yellow Tongue Coating

PROVIDER: PRJNA871372 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR21146816_1.fastq.gz	Fastqsanger.gz
	SRR21146816_2.fastq.gz	Fastqsanger.gz
	SRR21146817.fastq.gz	Fastqsanger.gz
	SRR21146818.fastq.gz	Fastqsanger.gz
	SRR21146819_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 106

Similar Datasets

Expression data of human peripheral blood leukocytes

Project description:Chronic hepatitis B (CHB) is a huge health burden in China, tongue diagnosis is the premise of personalized treatment of CHB by traditional Chinese medicine(TCM). The modern biological interpretation of pathological TCM tongue coating manifestation is unclear We performed transcriptional analysis in CHB patients with white tongue coating(WTC) or yellow tongue coating(YTC) to explain the potential inner biological differences

2019-08-08 | GSE135501 | GEO

Project description:Tongue coating bacteria

| PRJNA526319 | ENA

Lignocellulose fermentation to ethanol or lactate by giant panda gut microbiomes depends ultimately on pH rather than portion of bamboo

Project description:Giant panda are carnivorous bears which feed almost exclusively on plant biomass (i.e. bamboo). The potential contribution of its gut microbiome to lignocellulose degradation has been mostly investigated with cultivation-independent approaches. Recently, we reported on the first lab-scale cultivation of giant panda gut microbiomes and described their actual fermentation capacity. Fermentation of bamboo leaf using green dung resulted in a neutral pH, the main products being ethanol, lactate and H2. Fermentation of bamboo pith using yellow dung resulted in an acidic pH, the main product being lactate. Here, we cultivated giant panda gut microbiomes to test 1) the impact of mixed dung as inoculum; 2) the fermentation capacity of solid lignocellulose as opposed to organics-rich biofluids in the dung; 3) the artificial shift of pH from neutral to acidic on bamboo leaf fermentation. Our results indicate that i) gut microbiomes fermentation of solid lignocellulose contributes up to a maximum of 1/3 even in the presence of organics-rich biofluids; ii) alcohols are an important product of bamboo leaf fermentation at neutral pH; iii) aside hemicellulose, gut microbiomes may degrade plant cell membranes to produce glycerol; iv) pH, rather than portion of bamboo, ultimately determines fermentation profiles and gut microbiome assemblage.

2021-06-11 | PXD018503 | Pride

Giant panda (Ailuropoda melanoleuca) gut microbiomes degrade bamboo in distinct patterns: heterofermentation of green leaves to ethanol, lactate and acetate, and homofermentation of yellow pith to lactate

Project description:The iconic giant panda is an endangered species known worldwide for its peculiar dietary habits. While retaining the digestive system of a carnivore, the giant panda successfully moved into a diet almost exclusively based on bamboo. Digestion of lignocellulose is believed to be conducted solely by its gut microbiome, provided that no lignocellulose-degrading enzyme was found in the giant panda’s genome. Many reports focused on which lignocellulose component feeds the giant panda, while little effort was made to link the products of bamboo fermentation to the panda’s dietary choices. In the present study, fermentation of either green leaves or yellow pith was conducted in the laboratory using gut microbiomes derived from either green or yellow stools, respectively. Green leaves were fermented to ethanol, lactate and acetate, while yellow pith to lactate resembling, respectively, hetero/homo-fermentation patterns. Several microbial pathways (assessed by metaproteomics) related to hemicellulose rather than cellulose degradation. However, alpha-amylases (E.C. 3.2.1.1) from the giant panda itself were the most predominant enzyme (up to 60% of all metaproteins), indicating that they have a primary role in bamboo digestion. The distinct fermentation profiles resulting from digestion of selected portions of bamboo may be part of the feeding strategy of giant pandas.

2020-03-02 | PXD010872 | Pride

Project description:human tongue coating metagenome

| PRJNA422983 | ENA

Project description:Tongue coating microbiome sequencing

| PRJNA970271 | ENA

Project description:Different tongue coating microbiome

| PRJNA813359 | ENA

Project description:Type 2 Diabetes Mellitus Patients Treated with Metformin or Liraglutide Have Distinct Gut Microbiomes

| PRJNA387157 | ENA

Project description:Preschool children tongue coating sequence

| PRJNA642668 | ENA

human