Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Autonomous and non-autonomous functions of IL10RA in intestinal macrophages

ABSTRACT: Autonomous and non-autonomous functions of IL10RA in intestinal macrophages

PROVIDER: PRJNA872263 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Autonomous and non-autonomous functions of IL10RA in intestinal macrophages

Project description:To investigate the effects of cell-intrinsic loss of IL10RA on inflammatory macrophage function we performed gene expression profiling analysis using data from sorted lamina propria macrophages from bone marrow chimeric mice.

2022-12-22 | GSE211841 | GEO

Cell autonomous and non-autonomous interactions of a western-style diet and the vitamin D receptor in intestinal homeostasis and tumorigenesis

Project description:These data suggest that co-culture with macrophages increases expression of NDRG-1 in epithelial cell lines. The finding is confirmed in 2 human epithelial cell lines, and in tissue derived from mice genetically and dietetically altered to increase macrophage infiltration of the small and large intestinal epithelium. NDRG1 is identified as a potential mediator of macrophage effects on tumorigenesis in the large and small intestine. Array data is part of a larger study involving the effects of Vitamin D, in concert with macrophages, on intestinal homeostasis and tumorigenesis. Cells from mouse epithelial cell line CT26 were cultured either alone, or with RAW macrophages in a system which allowed no physical contact but exchange of soluble factors between the cell types. The experiment was peformed twice.

2014-03-12 | E-GEOD-55809 | biostudies-arrayexpress

Effect of co-culture with macrophages on two colon cancer cell lines.

Project description:These data suggest that co-culture with macrophages increases expression of NDRG-1 in epithelial cell lines. The finding is confirmed in 1 mouse epithelial cell line, and in tissue derived from mice genetically and dietetically altered to increase macrophage infiltration of the small and large intestinal epithelium. NDRG1 is identified as a potential mediator of macrophage effects on tumorigenesis in the large and small intestine. Array data is part of a larger study involving the effects of Vitamin D, in concert with macrophages, on intestinal homeostasis and tumorigenesis, entitled Cell autonomous and non-autonomous interactions of a western-style diet and the vitamin D receptor in intestinal homeostasis and tumorigenesis Cells from human colon cancer cell lines were cultured either alone, with Vitamin D3, with THP1 macrophages, or with THP1 macrophages and Vitamin D3, in a system which allowed no physical contact but exchange of soluble factors between the cell types.

2014-03-12 | E-GEOD-55810 | biostudies-arrayexpress

Cell non-autonomous regulation of chromosome segregation

Project description:Cell non-autonomous regulation of chromosome segregation

| PRJNA435867 | ENA

Cell autonomous and non-autonomous interactions of a western-style diet and the vitamin D receptor in intestinal homeostasis and tumorigenesis

2014-03-12 | GSE55809 | GEO

Effect of co-culture with macrophages on two colon cancer cell lines.

2014-03-12 | GSE55810 | GEO

Cell Autonomous and non-cell autonomous effects of neuronal Bin1 loss in vivo

Project description:Cell Autonomous and non-cell autonomous effects of neuronal Bin1 loss in vivo

| PRJNA558011 | ENA

AKT Inhibition Promotes Non-autonomous Cancer Cell Survival

Project description:AKT Inhibition Promotes Non-autonomous Cancer Cell Survival

| PRJNA292415 | ENA

WT and Ccr2-/- small intestinal macrophages

Project description:To better determine heterogeneity of small intestinal macrophages, CD64+ macrophages were sorted for single cell RNA sequencing

2023-08-18 | GSE234018 | GEO

Autonomous IL-36R Signaling positively modulates Neutrophil Anti-tumor Effector Functions

Project description:Autonomous IL-36R Signaling positively modulates Neutrophil Anti-tumor Effector Functions

| PRJNA863846 | ENA