Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Ribosome profiling of ZPR1-depleted S.cerevisiae cells

ABSTRACT: Ribosome profiling of ZPR1-depleted S.cerevisiae cells

PROVIDER: PRJNA875288 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Ribosome profiling of Aim29-knockout S.cerevisiae cells

Project description:Ribosome profiling of Aim29-knockout S.cerevisiae cells

| PRJNA955811 | ENA

Ribosome profiling of ZPR1-depleted S.cerevisiae cells

Project description:The aim of this study was to gain insight into the ribosome occupancy on different genes and codons in Zpr1-depleted cells vs. WT Zpr1 cells

2022-09-05 | GSE212389 | GEO

Transcriptome profiling time course of ZPR1-depleted S.cerevisiae cells

Project description:Transcriptome profiling time course of ZPR1-depleted S.cerevisiae cells

| PRJNA875287 | ENA

Transcriptome profiling time course of ZPR1-depleted S.cerevisiae cells

Project description:The aim of this study was to gain insight into the temporal dynamics of the transcriptome on depletion of the essntial eukaryotic gene ZPR1 in S.cerevisiae.

2022-09-05 | GSE212387 | GEO

Ribosome profiling experiment in control or Elp3 depleted B16 melanoma cells

Project description:Ribosome profiling experiment in control or Elp3 depleted B16 melanoma cells

| PRJNA438489 | ENA

Transcriptome profiling of Aim29-knockout S.cerevisiae cells

Project description:Transcriptome profiling of Aim29-knockout S.cerevisiae cells

| PRJNA954406 | ENA

Ribosome profiling of Aim29-knockout S.cerevisiae cells

Project description:The aim of this study was to gain insight into the ribosome occupancy on different genes and codons in AIM29 KO cells vs. wild-type cells

2023-04-17 | GSE229777 | GEO

Ribosome profiling of A549 cells depleted of RPLP1 and RPLP2 and infected with DENV.

Project description:We used ribosome profiling to evaluate viral and cellular translation in RPLP1/2-depleted cells. This revealed that ribosomes pause in the sequence coding for the N-terminus of the envelope protein, immediately downstream of sequences encoding two adjacent transmembrane domains (TMDs). RPLP1/2 function to enhance ribosome elongation at this position and increase viral protein stability, possibly by improving co-translational folding of DENV proteins. We also analyzed the effects of RPLP1/2 depletion on cellular translation. We find that RPLP1/2 moderately affects ribosome density for a small subset of cellular mRNAs. However, meta-analysis of ribosome positions on all cellular mRNAs revealed slightly increased accumulation of ribosomes downstream of start codons in RPLP1/2-depleted cells, suggesting that RPLP1/2 enhance elongation efficiency. Importantly, we found that ribosome density on mRNAs encoding multiple TMDs was disproportionately affected by RPLP1/2 knockdown, suggesting a role for RPLP1/2 in transmembrane protein biogenesis. Together, our findings reveal insights into the function of RPLP1/2 in DENV and cellular translation.

2019-06-21 | GSE133111 | GEO

Ribosome profiling of LS180 cells

Project description:Ribosome profiling of LS180 cells

| PRJNA870767 | ENA

Ribosome profiling of A549 cells depleted of RPLP1 and RPLP2 and infected with DENV.

Project description:Ribosome profiling of A549 cells depleted of RPLP1 and RPLP2 and infected with DENV.

| PRJNA549955 | ENA