Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

NHGRI GREGoR Consortium: Genomics Research to Elucidate the Genetics of Rare Disease

ABSTRACT: NHGRI GREGoR Consortium: Genomics Research to Elucidate the Genetics of Rare Disease

PROVIDER: PRJNA875550 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

NHGRI GREGoR Consortium: Genomics Research to Elucidate the Genetics of Rare Disease

Project description:NHGRI GREGoR Consortium: Genomics Research to Elucidate the Genetics of Rare Disease

| PRJNA875549 | ENA

Inherited Neuropathy Consortium Rare Disease Clinical Research Consortium (INC-RDCRC)

Project description:Inherited Neuropathy Consortium Rare Disease Clinical Research Consortium (INC-RDCRC)

| PRJNA994669 | ENA

Inherited Neuropathy Consortium Rare Disease Clinical Research Consortium (INC-RDCRC)

Project description:Inherited Neuropathy Consortium Rare Disease Clinical Research Consortium (INC-RDCRC)

| PRJNA994668 | ENA

NHGRI Clinical Sequencing Exploratory Research Program

Project description:NHGRI Clinical Sequencing Exploratory Research Program

| PRJNA158503 | ENA

NHGRI Menin ChIP-Chip

Project description:Multiple endocrine neoplasia type I (MEN1) is a familial cancer syndrome characterized primarily by tumors of multiple endocrine glands. The gene for MEN1 encodes a ubiquitously expressed tumor suppressor protein called menin. Menin was recently shown to interact with several components of a trithorax family histone methyltransferase complex including ASH2, Rbbp5, WDR5, and the leukemia proto-oncoprotein MLL. To elucidate menin's role as a tumor suppressor and gain insights into the endocrine-specific tumor phenotype in MEN1, we mapped the genomic binding sites of menin, MLL1, and Rbbp5, to approximately 20,000 promoters in HeLa S3, HepG2, and pancreatic islet cells using the strategy of chromatin-immunoprecipitation coupled with microarray analysis. We found that menin, MLL1, and Rbbp5 localize to the promoters of thousands of human genes but do not always bind together. These data suggest that menin functions as a general regulator of transcription. Keywords: ChIP/chip NHGRI Menin ChIP-Chip

2006-07-24 | E-GEOD-5357 | biostudies-arrayexpress

Lung Genomics Research Consortium

Project description:Lung Genomics Research Consortium

| PRJNA206539 | ENA

MicroRNA profiling of chronic lung disease for the Lung Genomics Research Consortium

Project description:These subjects were diagnosed as being controls or having interstitial lung disease (ILD) or chronic obstructive pulmonary disease (COPD) as determined by clinical history, CT scan, and surgical pathology. There was no intervention, these are cross-sectional data. All samples are from the Lung Tissue Research Consortium (LTRC) and are indexed by their LTRC tissue label.

2015-09-18 | GSE72967 | GEO

NHGRI Large Scale Sequencing Program

Project description:NHGRI Large Scale Sequencing Program

| PRJNA158497 | ENA

NHGRI Mendelian Disorders Sequencing Centers

Project description:NHGRI Mendelian Disorders Sequencing Centers

| PRJNA158501 | ENA

NHGRI CLL WES Relapse Study

Project description:NHGRI CLL WES Relapse Study

| PRJNA277245 | ENA