Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Methylated RNA immunoprecipitation sequencing (MeRIP-seq) and lncRNA sequencing (lncRNA-seq) of mouse embryonic brain tissue

PROVIDER: PRJNA879256 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR21739261_1.fastq.gz	Fastqsanger.gz
	SRR21739261_2.fastq.gz	Fastqsanger.gz
	SRR21739262_1.fastq.gz	Fastqsanger.gz
	SRR21739262_2.fastq.gz	Fastqsanger.gz
	SRR21739263_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 40

Similar Datasets

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3' UTRs and Near Stop Codons (OLD)

Project description:Here, we use a novel technique for locating regions of N6-adenosine methylation (m6A) throughout the transcriptome and present a profile of m6A sites in the mouse brain. Our use of methylated RNA immunoprecipitation combined with RNA-seq (MeRIP-Seq) identifies thousands of RNAs which contain m6A sites. In addition, we find that regions of m6A formation are particularly enriched near stop codons, which might provide clues into the potential funciton of this highly prevalent RNA modificaiton. Examination of m6A sites in murine brain RNA and human embryonic kidney cells.

2012-12-31 | E-GEOD-34734 | biostudies-arrayexpress

Global m6A-modified mRNAs in the uterus of wild-type mouse

Project description:Global m6A-modified mRNAs in the uterus of wild-type mouse were analyzed by using methylated RNA immunoprecipitation sequencing (MeRIP-seq)

2022-11-18 | GSE211521 | GEO

Global m6A-modified mRNAs in mouse uterus on gestational day 4 [meRIP-seq]

Project description:Global m6A-modified mRNAs in wild-type mouse uterus on gestational day 4 were analyzed by using methylated RNA immunoprecipitation sequencing (MeRIP-seq)

2024-04-12 | GSE263379 | GEO

Adenosine methylation is widespread throughout the transcriptome and prominent within 3' UTRs

2012-05-16 | E-GEOD-29714 | biostudies-arrayexpress

MeRIP-sequencing analysis of cerebral cortex in Down syndrome and controls

Project description:To explore the characteristics of m6A RNA modification in the Down syndrome brain, we collected cerebral cortex tissues of the fetuses diagnosed with Down syndrome and controls respectively, and performed an optimized methylated RNA immunoprecipitation combined with deep sequencing (MeRIP-seq).

2020-11-03 | GSE160689 | GEO

Screen of traumatic brain injury-associated genes from lncRNA m6A-modified transcriptomes in the cerebral cortex of mice after repetitive mild traumatic brain injury

Project description:N6-methyladenosine (m6A), a prevalent post-transcriptional modification in eukaryotic RNA, plays a significant role in regulating sensory experiences, learning, and injury in the mammalian central nervous system. However, the pattern of lncRNA m6A methylation in the mouse cortex following repetitive mild traumatic brain injury (rmTBI) has not been explored. This study conducted a genome-wide analysis of lncRNA m6A methylation in the mouse cortex using methylated RNA immunoprecipitation sequencing (MeRIP-Seq). Our analysis revealed 43,103 peaks were significantly upregulated or downregulated. Notably, the expression of m6A peaks indicated altered methylation and expression levels of 423 lncRNAs after rmTBI. In addition, employing METTL3 inhibitor STM2457 demonstrated that functional METTL3 was essential for repairing neural damage caused by rmTBI and influenced spatial learning and memory in rmTBI-model mice. Thus, the m6A methylation pattern of lncRNA in the mouse cortex after rmTBI identifies METTL3 as a potential intervention target for epigenetic modification following such injuries.

2025-01-22 | GSE287356 | GEO

Identification of N6-methyladenosine functions of YTHDF3 using MeRIP-seq analysis combined with transcription sequencing

Project description:We performed methylated RNA immunoprecipitation followed by sequencing (MeRIP–seq) combined with transcription sequencing to clarify the mechanism underlined YTHDF3 in CRC

2019-10-29 | GSE129716 | GEO

m6A MeRIP-seq of skeletal muscle during innervation and denervation

Project description:To assess the m6A methylome during denervation-induced muscle atrophy, the methylated RNA immunoprecipitation sequencing (MeRIP-seq) was performed.

2021-09-26 | GSE179178 | GEO

Effect of knockout of ALKBH5 on gene expression and m6A modifications during IRI in mice

Project description:To identify the direct m6A demethylation targets of ALKBH5 at the onset of renal IRI, we performed methylated RNA immunoprecipitation sequencing (MeRIP-seq) and RNA sequencing (RNA-seq) using RNA isolated from IRI mouse kidney of WT and KO mice 24h after I/R (WT n=3 vs. KO n=3)

2023-02-05 | GSE224289 | GEO

Alteration in m6A methylome of goat lung under PPRV infection

Project description:We report the application of MeRIP-seq (m6A-specific methylated RNA immunoprecipitation) for m6A site profiling of lung tissue under Peste des petits ruminants virus (PPRV) infection.

2022-12-05 | GSE190718 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data