Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

BGC-823 Cells: Control vs. BGC-823 Cells METTL3 Overexpressed

ABSTRACT: BGC-823 Cells: Control vs. BGC-823 Cells METTL3 Overexpressed

PROVIDER: PRJNA881250 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Differential gene expression between BGC-823/NC and BGC-823/MTA2, SGC-7901/NC and SGC-7901/shMTA2 cells

Project description:Metastasis associated 1 family, member 2 (MTA2) gene is classified to metastasis associated gene family. We have previously reported that MTA2 gene was overexpressed in gastric cancer tissues, correlating with tumor invasion, lymph node metastasis, and advanced TNM stage. MTA2 knockdown significantly inhibited gastric cancer cell invasion and metastasis. Yet, its molecular mechanisms are still unclear. The aim of this study is to investigate the molecular mechanisms of MTA2 in regulating malignant behaviors of gastric cancer. This experiment captures the expression data between BGC-823/NC and BGC-823/MTA2, SGC-7901/NC and SGC-7901/shMTA2 cells using Whole human genome microarray 4×44K (Design ID: 014850, Agilent technologies).

2015-04-08 | E-MTAB-3469 | biostudies-arrayexpress

BGC-823 Cells: Control vs. BGC-823 Cells METTL3 Overexpressed

Project description:METTL3-mediated RNA N6-methyladenosine (m6A) is the most prevalent modification participates in tumor initiation and progression via regulating expression of their target genes in cancers.. In this study, we conducted an analysis of m6A microarray in gastric cancer cells.

2022-09-17 | GSE213499 | GEO

Expression data from Human gastric cancer cells (BGC‐823)

Project description:The goal of this study is to analyze the expression data from Human gastric cancer cells (BGC‐823) followed by PGRN-downregulation and search potential therapeutic targets of diseases associated with Helicobacter pylori infection

2024-05-04 | GSE266076 | GEO

Expression data from Human gastric cancer cells (BGC‐823)

Project description:Expression data from Human gastric cancer cells (BGC‐823)

| PRJNA1105648 | ENA

Gene expression profiling of BGC-823 cells with or without PCDH9-Cter overexpression

Project description:Loss of Protocadherin 9 (PCDH9) is associated with the metastasis and the prognosis of gastric cancer patients, while the molecular mechanism of PCDH9-impaired gastric cancer metastasis remains unclear. Here we show that PCDH9 is cleaved in gastric cancer cells and intracellular domain of PCDH9 (PCDH9-Cter) translocates into nucleus. To decipher the mechanism underlying PCDH9-Cter-inhibited tumor cell migration, we performed RNA-Sequencing analysis for BGC-823 cells with or without PCDH9-Cter overexpression.

2024-02-21 | GSE248874 | GEO

Binding motif analysis of METTL3，WTAP in METTL3，WTAP overexpressed Human 293T cells

Project description:label the cells overexpressed Myc tagged METTL3 and Flag tagged WTAP with 4-SU, the RNA bound by METT3,WTAP can be got by Myc or Flag IP followed by RNA isolation by using the TRIzol (Invitrogen) reagent by following the company manual.the RNA was then used for library preparation using a TruSeq™ RNA Sample Prep Kit v2 (Illumina, San Diego, CA, USA) according to the manufacturer’s protocol.The libraries were sequenced using HiSeq2000 (Illumina) in single-read mode, creating reads with a length of 50 bp. Sequencing chemistry v2 (Illumina) was used and samples were multiplexed in two samples per lane. discovery of the binding motif of METTL3，WTAP in METTL3，WTAP overexpressed Human 293T cells

2014-01-16 | E-GEOD-50580 | biostudies-arrayexpress

Gene expression profiling of BGC-823 cells with or without PCDH9-Cter overexpression

Project description:Gene expression profiling of BGC-823 cells with or without PCDH9-Cter overexpression

| PRJNA1046162 | ENA

Paleofuran BGC

Project description:Paleofuran BGC

| PRJEB75212 | ENA

Binding motif analysis of METTL3，WTAP in METTL3，WTAP overexpressed Human 293T cells

2014-01-16 | GSE50580 | GEO

METTL3 promotes translation in human cancer cells

Project description:we find METTL3 associates with polyribosomes and promotes translation. METTL3 depletion inhibits translation, and both wild-type and catalytically inactive METTL3 promote translation when tethered to the 3' untranslated region (UTR) of a reporter mRNA. Mechanistically, METTL3 enhances mRNA translation through an interaction with the translation initiation machinery. m6A seq in A549 and H1299 cells, RNA seq in METTL3 knockdown cells

2016-07-03 | E-GEOD-76367 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data