Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Noncanonical Formation of SNX5 Gene-Derived Circular RNA Regulates Cancer Growth

ABSTRACT: Noncanonical Formation of SNX5 Gene-Derived Circular RNA Regulates Cancer Growth

PROVIDER: PRJNA883739 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR21689249_1.fastq.gz	Fastqsanger.gz
	SRR21689249_2.fastq.gz	Fastqsanger.gz
	SRR21689250_1.fastq.gz	Fastqsanger.gz
	SRR21689250_2.fastq.gz	Fastqsanger.gz
	SRR21689251_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 32

Similar Datasets

Noncanonical Formation of SNX5 Gene-Derived Circular RNA Regulates Cancer Growth

Project description:Noncanonical Formation of SNX5 Gene-Derived Circular RNA Regulates Cancer Growth

| PRJNA881998 | ENA

Noncanonical Formation of SNX5 Gene-Derived Circular RNA Regulates Cancer Growth

Project description:To investgate the funcitonal role of STAU1 on the formation of circSNX5. We performed gene expression profiling analysis using data obtained from RNA-seq of 2 different cells (replicate)

2024-06-19 | GSE214084 | GEO

Noncanonical Formation of SNX5 Gene-Derived Circular RNA Regulates Cancer Growth

2024-06-19 | GSE213634 | GEO

Kat2a regulates hippocampal memory formation

Project description:Kat2a regulates hippocampal memory formation

| PRJNA231958 | ENA

Epigenetic reader ZMYND11 noncanonical function restricts HNRNPA1-mediated stress granule formation and oncogenic activity.

Project description:Epigenetic reader ZMYND11 noncanonical function restricts HNRNPA1-mediated stress granule formation and oncogenic activity, To investigate the function of ZMYND11 in prostate cancer, We performed Co-IP and mass-spectometry (MS) analysis of ZMYND11.

2024-08-27 | PXD055219 |

Circular RNA cPLOD2 regulates pericyte function by targeting KLF4

Project description:Circular RNAs (circRNAs) are generated by back-splicing and control cellular signaling and phenotypes. Pericytes stabilize the capillary structure and play an important role in the formation and maintenance of new blood vessels. Here, we characterized hypoxia-regulated circRNAs in human pericytes and showed that circPLOD2 is induced by hypoxia and regulates pericyte functions. Silencing of circPLOD2 increased pericyte proliferation, endothelial-pericyte interactions and tube formation. Transcriptional profiling of circPLOD2-depleted cells and epigenomic analyses revealed widespread changes in gene expression and identified the regulation of the transcription factor KLF4 as a key effector of these changes. Importantly, overexpression of KLF4 was sufficient to reverse the effects on pericyte proliferation and endothelial-pericyte interactions observed after circPLOD2 depletion. Together, these data reveal a novel function of circPLOD2 in the control of pericyte proliferation and capillary formation and show that circPLOD2-mediated regulation of KLF4 significantly contributes to the transcriptional response to hypoxia.

2023-06-19 | GSE219237 | GEO

Circular RNA circZFPM2 regulates cardiomyocyte hypertrophy and survival

Project description:Circular RNA circZFPM2 regulates cardiomyocyte hypertrophy and survival

| PRJNA1085328 | ENA

Epigenetic reader ZMYND11 noncanonical function restricts HNRNPA1-mediated stress granule formation and oncogenic activity

Project description:Epigenetic reader ZMYND11 noncanonical function restricts HNRNPA1-mediated stress granule formation and oncogenic activity

| PRJNA1150951 | ENA

Circular RNA cPLOD2 regulates pericyte function by targeting KLF4

Project description:Circular RNA cPLOD2 regulates pericyte function by targeting KLF4

| PRJNA907784 | ENA

The Circular RNA Edis Regulates Neurodevelopment and Innate Immunity

Project description:The Circular RNA Edis Regulates Neurodevelopment and Innate Immunity