Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Rhodococcus aetherivorans strain:N1 | isolate:pure culture

ABSTRACT: Rhodococcus aetherivorans strain:N1 | isolate:pure culture Genome sequencing

PROVIDER: PRJNA885174 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Rhodococcus aetherivorans

Project description:Rhodococcus aetherivorans overview

| PRJNA71025 | ENA

Rhodococcus aetherivorans

Project description:Rhodococcus aetherivorans Genome sequencing

| PRJNA861906 | ENA

Rhodococcus aetherivorans I24

Project description:Rhodococcus aetherivorans I24 genome sequencing project

| PRJNA67297 | ENA

Transcriptional Response of Rhodococcus aetherivorans I24 to Polychlorinated Biphenyl-Contaminated Sediments.

Project description:We analyzed the transcriptional response of the actinomycete Rhodococcus aetherivorans I24 to biphenyl and polychlorinated biphenyls (PCBs). This species has not been extensively exposed to PCBs, as it was first isolated from a toluene contaminated aquifer, rather than a site contaminated with polychlorinated hydrocarbons. Using a microarray targeting 3524 genes, we assessed gene expression in minimal medium supplemented with various substrates (e.g. PCBs) and in both PCB-contaminated and non-contaminated sediment slurries. Relative to the reference condition (minimal medium supplemented with glucose), 408 genes were up-regulated in the various treatments. In medium and in sediment, PCBs elicited the up-regulation of a common set of 100 genes, including chaperones (groEL), a superoxide dismutase (sodA), alkyl hydroperoxide reductase protein C (ahpC), and a catalase/peroxidase (katG). Analysis of the R. aetherivorans I24 genome sequence identified orthologs of many of the genes in the canonical biphenyl pathway, but very few of these genes were up-regulated in response to PCBs or biphenyl. This study is one of the first which utilizes microarrays to assess the transcriptional response of a soil bacterium to a pollutant under conditions which more closely resemble the natural environment. Our results indicate that the transcriptional response of R. aetherivorans I24 to PCBs, in both medium and sediment, is primarily directed towards reducing oxidative stress, rather than catabolism. In addition, the identification of numerous genes expressed in contaminated soil specifically may have implications for the development of biosensors. Finally, comparative genomic and transcriptomic analyses suggest that the mere presence of orthologs of the required enzymes may not be sufficient to confer a vigorous biphenyl/PCB metabolism.

2010-03-20 | GSE17033 | GEO

Rhodococcus aetherivorans strain:ENV493

Project description:Rhodococcus aetherivorans strain:ENV493 Genome sequencing

| PRJNA967690 | ENA

Rhodococcus aetherivorans strain:L13

Project description:Rhodococcus aetherivorans strain:L13 Genome sequencing

| PRJNA995796 | ENA

Rhodococcus aetherivorans

Project description:Transcriptional Response of Rhodococcus aetherivorans I24 to Polychlorinated Biphenyl-Contaminated Sediments.

| PRJNA117799 | ENA

Rhodococcus aetherivorans strain:BCP1

Project description:Rhodococcus aetherivorans strain:BCP1 Genome sequencing and assembly