Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Microbial diversity of human skin affected by atopic dermatitis

PROVIDER: PRJNA890292 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR21895800_1.fastq.gz	Fastqsanger.gz
	SRR21895800_2.fastq.gz	Fastqsanger.gz
	SRR21895900_1.fastq.gz	Fastqsanger.gz
	SRR21895900_2.fastq.gz	Fastqsanger.gz
	SRR21897300_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 2462

Similar Datasets

Microarray transcriptome profiling of atopic dermatitis and psoriasis patients compared to healthy volunteers.

Project description:Characteization host-microbiome interactions in patients with allergic (model: atopic dermatitis) and autoimmune (model: psoriasis) diseases by integration of microarray transcriptome data with 16S microbial profiling. 6mm punch biopsies were collected from the skin of atopic dermatitis and psoriasis patients alongside healthy volunteers, and subjected to analysis using Affymetrix Human Gene ST 2.1 arrays.

2019-09-11 | E-MTAB-8149 | biostudies-arrayexpress

E-GEOD-36842

Project description:Transcription profiling by array of acute and chronic atopic dermatitis compared to normal skin

2025-01-24 | E-GEOD-36842 | ExpressionAtlas

E-GEOD-58558

Project description:Transcription profiling of skin samples from atopic dermatitis patients before and after treatment with cyclosporine A

2025-01-24 | E-GEOD-58558 | ExpressionAtlas

E-PROT-145

Project description:Atopic dermatitis epidermis PCT-DIA

2024-06-05 | E-PROT-145 | ExpressionAtlas

E-GEOD-32924

Project description:Transcription profiling by array of lesional and non-lesional skin from atopic dermatitis patients and healthy individuals

2025-01-24 | E-GEOD-32924 | ExpressionAtlas

Genomic profiling of the overlap phenotype between psoriasis and atopic dermatitis

Project description:Clinical overlaps between psoriasis and atopic dermatitis are sometimes undiscernible, and there is no consensus whether to treat the overlap phenotype as psoriasis or atopic dermatitis. We enrolled patients diagnosed with either psoriasis or atopic dermatitis, and clinically re-stratified them into classic psoriasis, classic atopic dermatitis, and the overlap phenotype between psoriasis and atopic dermatitis. We compared gene expression profiles of lesional and nonlesional skin biopsy tissues between the three comparison groups. Global mRNA expression and T-cell subset cytokine expression in the skin of the overlap phenotype were consistent with the profiles of psoriasis and different from the profiles of atopic dermatitis. Unsupervised k-means clustering indicated that the best number of distinct clusters for the total population of the three comparison groups was two, and the two clusters of psoriasis and atopic dermatitis were differentiated by gene expression. Our study suggests that clinical overlap phenotype between psoriasis and atopic dermatitis has dominant molecular features of psoriasis, and genomic biomarkers can differentiate psoriasis and atopic dermatitis at molecular levels in patients with a spectrum of psoriasis and atopic dermatitis.

2023-06-24 | GSE182740 | GEO

E-GEOD-27887

Project description:Transcription profiling by array of skin from patients with atopic dermatitis before and after treatment with narrow-band UVB radiation

2025-01-24 | E-GEOD-27887 | ExpressionAtlas

Genome-Wide Profiling of Lesional and Non-Lesional Skin from Atopic Dermatitis, Psoriasis, and Contact Dermatitis Skin

Project description:Genome-Wide Profiling of Lesional and Non-Lesional Skin from Atopic Dermatitis, Psoriasis, and Contact Dermatitis Skin

2020-06-23 | GSE153007 | GEO

Local and systemic changes in lipid profile as potential biomarkers for canine atopic dermatitis.

Project description:Lipids play a critical role in the skin as components of the epidermal barrier and as sig-naling molecules. Atopic dermatitis in dogs is associated with changes in the lipid composition of the skin, but whether these precede the onset of dermatitis or occur secondary to the dermatitis is unclear. We applied rapid lipid profiling mass spectrometry methods to skin and blood samples of dogs and determined changes following systemic treatment. Thirty control dogs and 30 atopic dogs with mild to moderate dermatitis were enrolled. Marked differences in lipid profiles were observed between control, nonlesional and lesional skin of dogs. Additionally, there were significant altera-tions in the lipid composition of the blood samples indicating systemic changes in lipid metabolism. Treatment with oclacitinib or lokivetmab resulted in a significant decrease of the disease clinical severity associated with changes in skin and blood lipids. A set of lipid features of the skin were selected as biomarkers that classified samples as control or atopic dermatitis with 95% accuracy, whereas blood lipids discriminated between control and atopic dogs with 82% accuracy. These data suggest that atopic dermatitis is a systemic disease and support the use of rapid lipid profiling to identify novel biomarkers.

2021-07-16 | MSV000087837 | MassIVE

N6-methyladenosine (m6A) modification in patients with psoriasis or atopic dermatitis [MeRIPseq_Human]

Project description:We analyzed m6A modifications in skin lesions of patients with psoriasis or atopic dermatitis (AD). The results of this study will help to gain insight into the molecular basis of m6A modification in inflammatory skin diseases such as psoriasis or atopic dermatitis.

2024-08-20 | GSE268744 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data