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Transcriptomic analysis in human 3D skin model injected with resorbable hyaluronic acid fillers reveals foreign body response [Perfectha]

ABSTRACT: Transcriptomic analysis in human 3D skin model injected with resorbable hyaluronic acid fillers reveals foreign body response [Perfectha]

PROVIDER: PRJNA892481 | ENA |

REPOSITORIES: ENA

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Transcriptomic analysis in human 3D skin model injected with resorbable hyaluronic acid fillers reveals foreign body response.

Project description:Transcriptomic analysis in human 3D skin model injected with resorbable hyaluronic acid fillers reveals foreign body response.

| PRJNA892921 | ENA

Transcriptomic analysis in human 3D skin model injected with resorbable hyaluronic acid fillers reveals foreign body response [RIVM]

Project description:Transcriptomic analysis in human 3D skin model injected with resorbable hyaluronic acid fillers reveals foreign body response [RIVM]

| PRJNA892479 | ENA

Transcriptomic analysis in human 3D skin model injected with resorbable hyaluronic acid fillers reveals foreign body response [Perfectha]

Project description:To unravel the molecular events caused by exposure to dermal fillers in a multi-cell type human 3D skin model and to link these events to the characteristics of the dermal fillers.

2022-11-16 | GSE216167 | GEO

Transcriptomic analysis in human 3D skin model injected with resorbable hyaluronic acid fillers reveals foreign body response [RIVM]

2022-11-16 | GSE216169 | GEO

Transcriptomic analysis in human 3D skin model injected with resorbable hyaluronic acid fillers reveals foreign body response.

Project description:This SuperSeries is composed of the SubSeries listed below.

2022-11-16 | GSE216279 | GEO

Spatial sequencing of Foreign body granuloma

Project description:Although macrophage-epithelioid cell (EPC)-giant cell (GC) differentiation is acknowledged in foreign body reaction (FBR), the exact molecular features remain elusive. To discover the molecular profiles of EPC and GC, we analyzed mouse sponge and silk FBRs by integrating single-cell RNA-sequencing (scRNA-seq) and spatial sequencing.

2022-05-17 | GSE203165 | GEO

Single cell 3' RNA sequencing of Foreign body granuloma

2022-05-17 | GSE203099 | GEO

Allometric tissue-scale forces activate mechanoresponsive immune cells to determine pathological foreign body response to biomedical implants

Project description:Allometric tissue-scale forces at the implant-tissue interface drive pathological foreign body response.

2023-06-05 | GSE227908 | GEO

Single-cell Analysis of Surface Topography-induced Foreign Body Response to Silicone Implants

Project description:Silicone-based medical devices are widely used in chronic implants and are generally perceived to be safe. However, immune-related complications including malignancies have recently been linked to textured breast implants. Here, we examine the influence of clinically approved breast implants surface features on host immune responses. Prosthetics with surface roughness of 0, 4, and 90 (Ra) were implanted in mammary fat pads of mice for 2 weeks and cells adjacent to the resulting tissue capsules were evaluated for foreign body immune responses using single-cell RNA-seq. Our findings identify a unique and finely tuned surface topography that is capable of modulating implant immunity to suppress foreign body response.

2021-05-28 | GSE164645 | GEO

Immunocompatible Elastomer with increased resistance to the foreign body response

Project description:Immunocompatible Elastomer with increased resistance to the foreign body response

| PRJNA1148948 | ENA