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Enterococcus ratti

ABSTRACT: Enterococcus ratti overview

PROVIDER: PRJNA89347 | ENA |

REPOSITORIES: ENA

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Dataset's files

Source:

			Action	DRS
	DRR015830_1.fastq.gz	Fastqsanger.gz
	DRR015830_2.fastq.gz	Fastqsanger.gz
	SRR554261_1.fastq.gz	Fastqsanger.gz
	SRR554261_2.fastq.gz	Fastqsanger.gz
	SRR684518_consensus.fastq.gz	Fastqsanger.gz

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Enterococcus ratti

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Strongyloides ratti molecular basis of parasitism

Project description:The genus Strongyloides spp. include important human parasites. There is also a well studied rodent model, S. ratti. Uniquely among parasitic nematodes, the Strongyloides life-cycle includes both a parasitic female stage and a genetically identical free-living female stage. Differences between these two female forms must be epigenetic, presumably controlled by altered transcription and translation. This is a project to compare the proteome and transcriptome of the parasitic and free-living females of S. ratti. From this we will define the genes and gene products of the parasitic female stage. This approach exploits the currently advanced S. ratti genome sequencing project. This work will give an understanding of the molecular basis of nematode parasitism, and so define new potential drug targets. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/

2013-06-11 | E-ERAD-151 | biostudies-arrayexpress

Transcriptome sequencing of Strongyloides ratti

Project description:Strongyloides ratti is a common gastro-intestinal parasite of the rat. The adult parasites are female only, about 2mm long and live in the mucosa of the small intestine. These parasites produce eggs that pass out of the host in its faeces. In the environment infective larval stages develop either directly or after a facultative sexual free-living adult generation. Infective larvae infect hosts by skin penetration.S. ratti is the laboratory analogue of the parasite of humans, S. stercoralis. S. stercoralis is a wide-spread parasite of humans, occurring principally in the tropics and sub-tropics: some 100-200 million people are infected worldwide. Infection of immunosuppressed individuals can result in disseminated strongyloidiasis, in which worms occur throughout the body. This can be fatal unless anti-Strongyloides therapy is given. Other species of Strongyloides parasitise a wide range of vertebrates. As part of the Strongyloides ratti genome project we are profiling the transcriptome of the parasite across its life cycle using RNA-Seq.. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/

2013-01-28 | E-ERAD-92 | biostudies-arrayexpress

Strongyloides ratti isolate:ED321

Project description:Strongyloides ratti isolate:ED321 Raw sequence reads

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Staphylococcus ratti strain:CCM 9025

Project description:Description of Staphylococcus ratti sp. nov.

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Transcription profiling of Strongyloides ratti free living vs parasitic females

Project description:In previous studies we have shown that the two adult females morphs of S. ratti have very different lifespans. This experiment was designed to try to identify differentially expressed genes in these two adult morphs that may account for these differing lifespans. The genes expressed by S. ratti parasitic females at day 6 p.i. were compared to the genes expressed by S. ratti free living females at 3 days 19 degrees C. This comparison was done using a microarray chip that is spotted with PCR fragments from the libraries that were generated from parasitic females extracted at day 6 and day 15 p.i., and a microarray chip that is spotted with PCR fragments from the libraries that were generated from free-living larval stages L1, L2 and infective L3s and from free-living males and females.

2008-05-24 | E-TABM-236 | biostudies-arrayexpress

Pelistega ratti strain:NLN82

Project description:Pelistega ratti strain:NLN82 Genome sequencing and assembly

| PRJNA575703 | ENA