Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Methylorubrum rhodesianum

ABSTRACT: Complete genome sequence of Methylorubrum sp. MB200, a Methylotrophic bacteria isolate from a household biodigester

PROVIDER: PRJNA894144 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR22061322_subreads.fastq.gz	Fastqsanger.gz
	SRR22062080_1.fastq.gz	Fastqsanger.gz
	SRR22062080_2.fastq.gz	Fastqsanger.gz
	SRR22062081_1.fastq.gz	Fastqsanger.gz
	SRR22062081_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 13

Similar Datasets

Genome-wide transcription start sites mapping in Methylorubrum grown using dichloromethane and methanol

Project description:Dichloromethane (DCM, methylene chloride) is a toxic halogenated volatile organic compound massively used for industrial applications, and consequently often detected in the environment as a major pollutant. DCM biotransformation offers a sustainable decontamination strategy of polluted sites. Among methylotrophic bacteria able to use DCM as sole source of carbon and energy for growth, Methylorubrum extorquens DM4 (formerly named Methyobacterium extorquens) is a longstanding reference Alphaproteobacteria strain. Here, its primary transcriptome was obtained using a differential RNA-seq (dRNA-seq) approach to provide the first transcription start site (TSS) genome-wide landscape of a methylotroph using DCM.

2022-06-27 | E-MTAB-11726 | biostudies-arrayexpress

Methylorubrum sp. GM97

Project description:Complete Genome Sequence of Methylorubrum sp. Strain GM97

| PRJDB13504 | ENA

Methylorubrum

Project description:Methylorubrum sp. overview

| PRJNA686469 | ENA

Formaldehyde-responsive proteins, TtmR and EfgA, reveal a tradeoff between formaldehyde resistance and efficient transition to methylotrophy in Methylorubrum extorquens

Project description:In order for bacteria to thrive, they must be well-adapted to their environmental niche, which may involve specialized metabolism, timely adaptation to shifting environments, and/or the ability to mitigate numerous stressors. These attributes are highly dependent on cellular machinery that can sense both the external and intracellular environment. Methylorubrum extorquens is an extensively studied facultative methylotroph, an organism that can use single-carbon compounds as their sole source of carbon and energy. In methylotrophic metabolism, carbon flows through formaldehyde as a central metabolite; thus, formaldehyde is both an obligate metabolite and a metabolic stressor. Via the one-carbon dissimilation pathway, free formaldehyde is rapidly incorporated by formaldehyde activating enzyme (Fae), which is constitutively expressed at high levels. In the presence of elevated formaldehyde levels, a recently identified formaldehyde-sensing protein, EfgA, induces growth arrest. Herein, we describe TtmR, a formaldehyde-responsive transcription factor that, like EfgA, modulates formaldehyde resistance. It is a member of the MarR family of transcription factors and impacts the expression of 75 genes distributed throughout the genome, many of which are themselves transcription factors and/or involved in stress response, including efgA. Notably, when M. extorquens is adapting its metabolic network during the transition to methylotrophy, efgA and ttmR mutants experience an imbalance in formaldehyde production and a notable growth delay. Although methylotrophy necessitates that M. extorquens maintain a relatively high level of formaldehyde tolerance, this work reveals a tradeoff between formaldehyde resistance and the efficient transition to methylotrophic growth and suggests that TtmR and EfgA play a pivotal role in maintaining this balance.

2021-03-11 | GSE159711 | GEO

Methylorubrum sp. POS3

Project description:Methylorubrum sp. POS3 Genome sequencing

| PRJNA906299 | ENA

Methylorubrum sp. DB1722

Project description:Methylorubrum sp. DB1722 Genome sequencing and assembly

| PRJNA496242 | ENA

Methylorubrum sp. B1-46

Project description:Methylorubrum sp. B1-46 Genome sequencing and assembly

| PRJNA781798 | ENA

Methylorubrum pseudosasae

Project description:Methylorubrum pseudosasae overview