Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Spatial epigenome-transcriptome co-profiling of mammalian tissues [spatial CUT&Tag]

ABSTRACT: Spatial epigenome-transcriptome co-profiling of mammalian tissues [spatial CUT&Tag]

PROVIDER: PRJNA896927 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR22141530_1.fastq.gz	Fastqsanger.gz
	SRR22141530_2.fastq.gz	Fastqsanger.gz
	SRR22141531_1.fastq.gz	Fastqsanger.gz
	SRR22141531_2.fastq.gz	Fastqsanger.gz
	SRR22141532_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 8

Similar Datasets

Spatial epigenome-transcriptome co-profiling of mammalian tissues [spatial CUT&Tag]

Project description:We present spatially resolved high-spatial-resolution genome-wide co-mapping of epigenome and transcriptome by simultaneously profiling of chromatin accessibility and gene expression (spatial-ATAC-RNA-seq), as well as histone modification and gene expression (spatial-CUT&Tag-RNA-seq) on the same tissue section at cellular level by combining the microfluidic deterministic barcoding strategy in DBiT-seq and the chemistry used in ATAC-seq/CUT&Tag.

2023-01-29 | GSE217091 | GEO

Spatial epigenome-transcriptome co-profiling of mammalian tissues [CUT&TAG]

2023-01-29 | GSE205051 | GEO

Spatial epigenome-transcriptome co-profiling of mammalian tissues [CUT&TAG]

Project description:Spatial epigenome-transcriptome co-profiling of mammalian tissues [CUT&TAG]

| PRJNA843459 | ENA

Spatial epigenome-transcriptome co-profiling of mammalian tissues

2023-01-29 | GSE218593 | GEO

Spatial epigenome-transcriptome co-profiling of mammalian tissues [RNA-Seq]

2023-01-29 | GSE205054 | GEO

Spatial epigenome-transcriptome co-profiling of mammalian tissues [ATAC-Seq]

2023-01-29 | GSE205052 | GEO

Spatial epigenome-transcriptome co-profiling of mammalian tissues [Human RNA-Seq]

2023-01-29 | GSE205181 | GEO

Spatial epigenome-transcriptome co-profiling of mammalian tissues [Human ATAC-Seq]

2023-01-29 | GSE205180 | GEO

Spatial-CUT&Tag: Spatially resolved chromatin modification profiling at the cellular level

Project description:Spatial omics emerged as a new frontier of biological and biomedical research. Here, we present spatial-CUT&Tag for spatially resolved genome-wide profiling of histone modifications by combining in situ CUT&Tag chemistry, microfluidic deterministic barcoding, and next-generation sequencing. Spatially resolved chromatin states in mouse embryos revealed tissue-type-specific epigenetic regulations in concordance with ENCODE references and provide spatial information at tissue scale. Spatial-CUT&Tag revealed epigenetic control of the cortical layer development and spatial patterning of cell types determined by histone modification in mouse brain. Single-cell epigenomes can be derived in situ by identifying 20-micrometer pixels containing only one nucleus using immunofluorescence imaging. Spatial chromatin modification profiling in tissue may offer new opportunities to study epigenetic regulation, cell function, and fate decision in normal physiology and pathogenesis.

2022-02-10 | GSE165217 | GEO

Spatial epigenome-transcriptome co-profiling of mammalian tissues

Project description:Spatial epigenome-transcriptome co-profiling of mammalian tissues

| PRJNA904377 | ENA